Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir

AC Stabell, NR Meyerson, RC Gullberg, AR Gilchrist… - Elife, 2018 - elifesciences.org
Human dengue viruses emerged from primate reservoirs, yet paradoxically dengue does not
reach high titers in primate models. This presents a unique opportunity to examine the …

Trio‐binned genomes of the woodrats Neotoma bryanti and Neotoma lepida reveal novel gene islands and rapid copy number evolution of xenobiotic metabolizing …

R Greenhalgh, ML Holding, TJ Orr… - Molecular Ecology …, 2022 - Wiley Online Library
The genomic architecture underlying the origins and maintenance of biodiversity is an
increasingly accessible feature of species, due in large part to third‐generation sequencing …

Role of cytochrome P450 2B sequence variation and gene copy number in facilitating dietary specialization in mammalian herbivores

S Kitanovic, TJ Orr, D Spalink, GB Cocke… - Molecular …, 2018 - Wiley Online Library
Abstract Theory postulates that dietary specialization in mammalian herbivores is enabled
by a specialized set of liver enzymes that process the high concentrations of similar plant …

Terpenes may serve as feeding deterrents and foraging cues for mammalian herbivores

MM Skopec, RP Adams, JP Muir - Journal of chemical ecology, 2019 - Springer
Terpenes, volatile plant secondary compounds produced by woody plants, have historically
been thought to act as feeding deterrents for mammalian herbivores. However, three …

Signatures of adaptive divergence among populations of an avian species of conservation concern

SJ Zimmerman, CL Aldridge, KP Oh… - Evolutionary …, 2019 - Wiley Online Library
Understanding the genetic underpinning of adaptive divergence among populations is a key
goal of evolutionary biology and conservation. Gunnison sage‐grouse (Centrocercus …

Using the specialization framework to determine degree of dietary specialization in a herbivorous woodrat

MM Skopec, KD Kohl, K Schramm, JR Halpert… - Journal of chemical …, 2015 - Springer
To be considered a dietary specialist, mammalian herbivores must consume large quantities
of a plant species considered “difficult” with respect to nutrient or toxin content, and possess …

[PDF][PDF] Comparison of leaf terpenoids and tannins in Juniperus osteosperma from woodrat (Neotoma stephensi) browsed and not-browsed trees

RP Adams, MM Skopec, JP Muir - Phytologia, 2016 - researchgate.net
Neotoma lepida (woodrat) browses on the leaves of Juniperus osteosperma near Dugway,
UT. A comparison between woodrat (N. lepida) browsed and not-browsed Juniperus …

Mammalian cytochrome P450 biodiversity: Physiological importance, function, and protein and genomic structures of cytochromes P4502B in multiple species of …

MM Skopec, JR Halpert, MD Dearing - Advances in Pharmacology, 2022 - Elsevier
The vast diversity of cytochrome P450 enzymes in mammals has been proposed to result in
large measure from plant-animal warfare, whereby evolution of chemical defenses such as …

Cytochrome P450 2B diversity in a dietary specialist—the red tree vole (Arborimus longicaudus)

S Kitanovic, CA Marks-Fife, QA Parkes… - Journal of …, 2018 - academic.oup.com
Although herbivores rely on liver enzymes to biotransform plant secondary metabolites
ingested in plant-based diets, only a few enzymes from a handful of species have been …

Trio-binned genomes of the woodrats Neotoma bryanti and N. lepida reveal novel gene islands and rapid copy number evolution of xenobiotic metabolizing …

R Greenhalgh, ML Holding, TJ Orr, JB Henderson… - bioRxiv, 2021 - biorxiv.org
The genomic architecture underlying the origins and maintenance of biodiversity is an
increasingly accessible feature of species, due in large part to third-generation sequencing …