Abstract The Biomarkers of Nutrition for Development (BOND) project is designed to provide
evidence-based advice to anyone with an interest in the role of nutrition in health …

▪ Abstract Choline is an essential nutrient needed for the structural integrity and signaling
functions of cell membranes; for normal cholinergic neurotransmission; for normal muscle …

DNA methylation influences the expression of some genes and depends upon the
availability of methyl groups from S-adenosylmethionine (SAM). Dietary methyl groups …

Evidence is growing that optimal dietary intake of folate and choline (both involved in one-
carbon transfer or methylation) is important for successful completion of fetal development …

During the fifteen years since the bestselling first edition of Folate in Health and Disease
was published, there have been thousands of new research studies related to folate and its …

Epigenetic marking on genes can determine whether or not genes are expressed.
Epigenetic regulation is mediated by the addition of methyl groups to DNA cytosine bases, of …

An association between hyperlipidemia and hyperhomocysteinemia (HHCY) has been
suggested. This link is clinically important in management of vascular risk factors especially …

Background: A high homocysteine concentration is a potential risk factor for cardiovascular
disease that can be reduced through betaine supplementation. Choline is the precursor for …

Excess vitamin intake during pregnancy leads to obesogenic phenotypes, and folic acid
accounts for many of these effects in male, but not in female, offspring. These outcomes may …

Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins; however,
not yet officially defined as a B vitamin. It is important in the synthesis of phospholipid …