Entorhinal cortex (EC), thought to be the location of the earliest lesions in Alzheimer's
disease (AD), has been widely studied in recent years. With the irreversible pathological …

Many studies of the human brain have explored the relationship between cortical thickness
and cognition, phenotype, or disease. Due to the subjectivity and time requirements in …

Animal and human autopsy studies suggest that subfields of the hippocampal formation are
differentially affected by neuropsychiatric diseases. Therefore, subfield volumes may be …

Aconsistent perception in the past 60 years has been that many elderly patients have
persistent cognitive decline after surgery and anesthesia. Particularly, cardiac surgery and …

Longitudinal studies of development and disease in the human brain have motivated the
acquisition of large neuroimaging data sets and the concomitant development of robust …

The medial temporal lobe (MTL) plays a key role in learning, memory, spatial navigation,
emotion, and social behavior. The improvement of noninvasive neuroimaging techniques …

Associative memory involves remembering relations between items of information and is
critically dependent on the hippocampus, a brain structure that shows early changes in …

The cortical thickness has been used as a biomarker to assess different cerebral conditions
and to detect alterations in the cortical mantle. In this work, we compare methods from the …

Background: Reduced preoperative cognition is a risk factor for postoperative delirium. The
significance for type of preoperative cognitive deficit, however, has yet to be explored and …

Automated segmentation of hippocampal (HC) subfields from magnetic resonance imaging
(MRI) is gaining popularity, but automated procedures that afford high speed and …