Hypoxia-mimicking scaffolds with controlled release of DMOG and PTHrP to promote cartilage regeneration via the HIF-1α/YAP signaling pathway

L Chen, X Huang, H Chen, D Bao, X Su, L Wei… - International Journal of …, 2023 - Elsevier
Efficiently driving chondrogenic differentiation of bone marrow mesenchymal stem cells
(BMSCs) while avoiding undesired hypertrophy remains a challenge in the field of cartilage …

Human‐based new approach methodologies to accelerate advances in nutrition research

M Cassotta, D Cianciosi, M Elexpuru‐Zabaleta… - Food …, 2024 - Wiley Online Library
Much of nutrition research has been conventionally based on the use of simplistic in vitro
systems or animal models, which have been extensively employed in an effort to better …

A dynamic air–liquid interface system for in vitro mimicking of the nasal mucosa

E Capuana, A Fucarino, S Burgio, G Intili… - Biotechnology and …, 2022 - Wiley Online Library
The development of an in vitro 3D model for the growth of the nasal mucosa cells can
improve the therapy and the study of pathological states for subjects with chronic airway …

Development of a Novel in vitro System for Biomedical Applications

ME Lombardo - 2022 - search.proquest.com
The use of animals in science and medicine research has significantly benefited human
beings. Although their physiology does not identically mimic the human body, they act as …