Curcumin in liver diseases: a systematic review of the cellular mechanisms of oxidative stress and clinical perspective

MH Farzaei, M Zobeiri, F Parvizi, FF El-Senduny… - Nutrients, 2018 - mdpi.com
Oxidative stress has been considered a key causing factor of liver damage induced by a
variety of agents, including alcohol, drugs, viral infections, environmental pollutants and …

Protective effect of curcumin against heavy metals-induced liver damage

WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014 - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Controlled release of curcumin from electrospun fiber mats with antibacterial activity

MM Mahmud, S Zaman, A Perveen, RA Jahan… - Journal of Drug Delivery …, 2020 - Elsevier
Nanofibers of polyvinyl alcohol (PVA) loaded with different concentration of curcumin was
fabricated through electrospinning process. The nanofiber mats were crosslinked through …

[HTML][HTML] Inside and beyond color: Comparative overview of functional quality of tomato and watermelon fruits

R Ilahy, I Tlili, MW Siddiqui, C Hdider… - Frontiers in Plant …, 2019 - frontiersin.org
The quali-quantitative evaluation and the improvement of the levels of plant bioactive
secondary metabolites are increasingly gaining consideration by growers, breeders and …

Curcumin attenuates on carbon tetrachloride-induced acute liver injury in mice via modulation of the Nrf2/HO-1 and TGF-β1/Smad3 pathway

X Peng, C Dai, Q Liu, J Li, J Qiu - Molecules, 2018 - mdpi.com
This study aimed to investigate the protective effect of curcumin against carbon tetrachloride
(CCl4)-induced acute liver injury in a mouse model, and to explain the underlying …

Polyphenols: Major regulators of key components of DNA damage response in cancer

M Majidinia, A Bishayee, B Yousefi - DNA repair, 2019 - Elsevier
DNA fidelity is constantly endangered by various types of intrinsic damages and extrinsic
damages. Cells that are affected by DNA damage employ a specific, intricate, and …

[HTML][HTML] Curcumin protects osteoblasts from oxidative stress-induced dysfunction via GSK3β-Nrf2 signaling pathway

X Li, Y Chen, Y Mao, P Dai, X Sun, X Zhang… - … in Bioengineering and …, 2020 - frontiersin.org
Osteoblasts dysfunction, induced by oxidative stress (OS), is one of major pathological
mechanisms for osteoporosis. Curcumin (Cur), a bioactive antioxidant compound, isolated …

Curcumin attenuates colistin-induced neurotoxicity in N2a cells via anti-inflammatory activity, suppression of oxidative stress, and apoptosis

C Dai, GD Ciccotosto, R Cappai, S Tang, D Li… - Molecular …, 2018 - Springer
Neurotoxicity is an unwanted side-effect seen in patients receiving therapy with the “last-
line” polymyxin antibiotics. This is the first study to show that colistin-induced neurotoxicity in …

Is there a role for curcumin supplementation in the treatment of non-alcoholic fatty liver disease? The data suggest yes

N Amel Zabihi, M Pirro, TP Johnston… - Current …, 2017 - ingentaconnect.com
Nonalcoholic fatty liver disease (NAFLD) is the most common type of liver disease. NAFLD is
considered a multifactorial disease and a clinically relevant hepatic manifestation of …

Curcumin prevents mitochondrial dynamics disturbances in early 5/6 nephrectomy: Relation to oxidative stress and mitochondrial bioenergetics

OE Aparicio‐Trejo, E Tapia, E Molina‐Jijón… - Biofactors, 2017 - Wiley Online Library
Abstract Five‐sixths nephrectomy (5/6NX) is a widely used model to study the mechanisms
leading to renal damage in chronic kidney disease (CKD). However, early alterations on …