Enterococci have been recognized as important hospital-acquired pathogens in recent
years, and isolates of E. faecalis and E. faecium are the third-to fourth-most prevalent …

NMR spectroscopy is a key method for studying the structure and dynamics of (large)
multidomain proteins and complexes in solution. It plays a unique role in integrated …

Extrachromosomal elements are ubiquitous in the prokaryotic world and play important roles
in the adaptation and survival of cell populations, especially in changing environments …

Toxin–antitoxin (TA) loci consist of two genes: a stable toxin whose overexpression kills the
cell or causes growth stasis and an unstable antitoxin that neutralizes the toxin action …

Bacterial toxin–antitoxin (TA) systems have received increasing attention for their diverse
identities, structures, and functional implications in cell cycle arrest and survival against …

Chlorhexidine is a bisbiguanide antiseptic used for infection control. Vancomycin-resistant
E. faecium (VREfm) is among the leading causes of hospital-acquired infections. VREfm …

Solvent paramagnetic relaxation enhancement (sPRE) is a versatile nuclear magnetic
resonance (NMR)-based method that allows characterization of the structure and dynamics …

Both temperate and obligately lytic phages have crucial roles in the biology of staphylococci.
While superinfection exclusion among closely related temperate phages is a well …

Small proteins comprising less than 100 amino acids have been often ignored in bacterial
genome annotations. About 10 years ago, focused efforts started to investigate whole …

We report a functional type I toxin-antitoxin (TA) module expressed by a human pathogen,
Staphylococcus aureus. TA systems consist of stable toxins and labile antitoxins encoded …