Statins are the gold-standard treatment for the prevention of primary and secondary
cardiovascular disease, which is the leading cause of mortality worldwide. Despite the safety …

Glucose and cholesterol engage in almost all human physiological activities. As the primary
energy substance, glucose can be assimilated and converted into diverse essential …

BACKGROUND: Dyslipidemia is treated effectively with statins, but treatment has the
potential to induce new-onset type-2 diabetes. Gut microbiota may contribute to this outcome …

Background: Acute ischemic strokes (AIS) are a common cause of morbidity, mortality, and
disability. The serum biomarker S100β correlates with poor neurological outcomes in the …

Context Nonalcoholic fatty liver disease (NAFLD) has emerged as a public health issue,
while no drugs have been specifically approved for treatment. Objective This study aimed to …

Background Thyroid eye disease (TED) is a vision-threatening autoimmune disorder. Orbital
tissue fibrosis leading to intractable complications remains a troublesome issue in TED …

Depletion of coenzyme Q (CoQ) is associated with disease, ranging from myopathy to heart
failure. To induce a CoQ deficit, C2C12 myotubes were incubated with high dose …

Statins, the drugs for the treatment of dyslipidemia, have been suggested to impact insulin
sensitivity, resulting in pancreatic β-cell dysfunction, and consequently, lead to new onset of …

Wnt 信号通路与大脑发育和中枢神经系统成熟密切相关, 参与神经突触调节和重塑,
在突触可塑性和学习记忆中有重要作用. 该文综述了Wnt 信号在突触结构与功能中的作用, Wnt …

Statins are the cornerstone for primary and secondary prevention of cardiovascular disease
as they have been proven to reduce cardiovascular morbidity and mortality. Statins act by …