Low-dose aspirin for the prevention of atherothrombosis
C Patrono, LA García Rodríguez… - … England Journal of …, 2005 - Mass Medical Soc
This review considers the role of low-dose aspirin for the prevention of atherothrombosis,
discussing the molecular mechanism of action of aspirin as well as clinical and …
discussing the molecular mechanism of action of aspirin as well as clinical and …
Expert consensus document on the use of antiplatelet agents: The Task Force on the Use of Antiplatelet Agents in Patients With Atherosclerotic Cardiovascular …
The role of aspirin and other platelet-active drugs in the treatment and prevention of
atherothrombosis has been reviewed recently by the Sixth American College of Chest …
atherothrombosis has been reviewed recently by the Sixth American College of Chest …
Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
Background—We studied whether aspirin resistance, defined as failure of suppression of
thromboxane generation, increases the risk of cardiovascular events in a high-risk …
thromboxane generation, increases the risk of cardiovascular events in a high-risk …
A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease
PA Gum, K Kottke-Marchant, PA Welsh, J White… - Journal of the American …, 2003 - jacc.org
Objectives: This study was designed to determine if aspirin resistance is associated with
clinical events. Background: Aspirin resistance, defined by platelet function testing and …
clinical events. Background: Aspirin resistance, defined by platelet function testing and …
Platelet-active drugs: the relationships among dose, effectiveness, and side effects: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
This article discusses platelet active drugs as part of the Seventh American College of Chest
Physicians Conference on Antithrombotic and Thrombolytic Therapy: Evidence-Based …
Physicians Conference on Antithrombotic and Thrombolytic Therapy: Evidence-Based …
Platelet-active drugs: the relationships among dose, effectiveness, and side effects
Abbreviations: ACE trial Acetylsalicylic Acid and Carotid Endarterectomy; ADP adenosine
diphosphate; AMP adenosine monophosphate; CAPRIE study Clopidogrel vs Aspirin in …
diphosphate; AMP adenosine monophosphate; CAPRIE study Clopidogrel vs Aspirin in …
Overexpression of Functionally Coupled Cyclooxygenase-2 and Prostaglandin E Synthase in Symptomatic Atherosclerotic Plaques as a Basis of Prostaglandin E2 …
F Cipollone, C Prontera, B Pini, M Marini, M Fazia… - Circulation, 2001 - Am Heart Assoc
Background—Studies have implicated a role for prostaglandin (PG) E2-dependent matrix
metalloproteinase (MMP) biosynthesis in the rupture of atherosclerotic plaque …
metalloproteinase (MMP) biosynthesis in the rupture of atherosclerotic plaque …
Cyclooxygenase-1 and-2–dependent prostacyclin formation in patients with atherosclerosis
O Belton, D Byrne, D Kearney, A Leahy, DJ Fitzgerald - Circulation, 2000 - Am Heart Assoc
Background—The formation of prostacyclin (PGI2), thromboxane (TX) A2, and isoprostanes
is markedly enhanced in atherosclerosis. We examined the relative contribution of …
is markedly enhanced in atherosclerosis. We examined the relative contribution of …
Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers
Background and Purpose—Aspirin resistance may be relatively common and associated
with adverse outcome. Meta-analysis has clearly shown that 75 mg plain aspirin is the …
with adverse outcome. Meta-analysis has clearly shown that 75 mg plain aspirin is the …
Effectiveness and tolerance of anti‐inflammatory drugs' add‐on therapy in major mental disorders: a systematic qualitative review
Objective To provide a systematic review of the literature regarding the efficacy of anti‐
inflammatory drugs in three major mental disorders [major depressive disorder (MDD) …
inflammatory drugs in three major mental disorders [major depressive disorder (MDD) …