[HTML][HTML] Lipogenic effects of androgen signaling in normal and malignant prostate
Prostate cancer is an androgen-dependent cancer with unique metabolic features compared
to many other solid tumors, and typically does not exhibit the “Warburg effect”. During …
to many other solid tumors, and typically does not exhibit the “Warburg effect”. During …
FABP5 coordinates lipid signaling that promotes prostate cancer metastasis
G Carbonetti, T Wilpshaar, J Kroonen, K Studholme… - Scientific reports, 2019 - nature.com
Prostate cancer (PCa) is defined by dysregulated lipid signaling and is characterized by
upregulation of lipid metabolism-related genes including fatty acid binding protein 5 …
upregulation of lipid metabolism-related genes including fatty acid binding protein 5 …
The gut microbiome-prostate cancer crosstalk is modulated by dietary polyunsaturated long-chain fatty acids
G Lachance, K Robitaille, J Laaraj, N Gevariya… - Nature …, 2024 - nature.com
The gut microbiota modulates response to hormonal treatments in prostate cancer (PCa)
patients, but whether it influences PCa progression remains unknown. Here, we show a …
patients, but whether it influences PCa progression remains unknown. Here, we show a …
Spatial modeling of prostate cancer metabolic gene expression reveals extensive heterogeneity and selective vulnerabilities
Spatial heterogeneity is a fundamental feature of the tumor microenvironment (TME), and
tackling spatial heterogeneity in neoplastic metabolic aberrations is critical for tumor …
tackling spatial heterogeneity in neoplastic metabolic aberrations is critical for tumor …
Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia
The interaction of germline variation and somatic cancer driver mutations is under-
investigated. Here we describe the genomic mitochondrial landscape in adult acute myeloid …
investigated. Here we describe the genomic mitochondrial landscape in adult acute myeloid …
The role of lipid metabolism in cancer radioresistance
D An, D Zhai, C Wan, K Yang - Clinical and Translational Oncology, 2023 - Springer
Radiotherapy is one of the main therapies for cancer. The process leading to
radioresistance is still not fully understood. Cancer radiosensitivity is related to the DNA …
radioresistance is still not fully understood. Cancer radiosensitivity is related to the DNA …
The ferroptosis-related long non-coding RNAs signature predicts biochemical recurrence and immune cell infiltration in prostate cancer
C Liu, Y Gao, J Ni, S Chen, Q Hu, C Wang, M Hu… - BMC cancer, 2022 - Springer
Background Findings from numerous studies have revealed that ferroptosis is closely
related to tumorigenesis and immune cell infiltration. Long non-coding RNAs (lncRNAs) are …
related to tumorigenesis and immune cell infiltration. Long non-coding RNAs (lncRNAs) are …
Physical resistance training-induced changes in lipids metabolism pathways and apoptosis in prostate
Background Altered lipid metabolism is an important characteristic of neoplastic cells, with
androgens and growth factors being major regulatory agents of the lipid metabolism …
androgens and growth factors being major regulatory agents of the lipid metabolism …