Abstract The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A–F, plays
crucial roles in host defense against microbial organisms and in the development of …

Atopic dermatitis (AD) is the most common dermatological disease of childhood. Many
children with AD have asthma and AD shares regions of genetic linkage with psoriasis …

Inflammation participates in host defenses against infectious agents and contributes to the
pathophysiology of many diseases. IL-17 is a well-known proinflammatory cytokine that …

The type I interferon (IFN) system is persistently activated in systemic lupus erythematosus
(SLE) and many other systemic autoimmune diseases. Studies have shown an association …

Langerhans cell histiocytosis (LCH) is a group of granulomatous disorders in which
abnormal Langerhans cells proliferate as either a localized lesion in a single bone or …

The most fatal viral pathogen in olive flounder Paralichthys olivaceus, is viral hemorrhagic
septicemia virus, which afflicts over 48 species of freshwater and marine fish. Here, we …

Th17 is a lymphocyte T helper (Th) subpopulation relevant in the control and regulation of
the immune response characterized by the production of interleukin (IL)-17. This crucial …

Abstract Interleukin-17 receptors (IL17Rs) mediate the activation of several downstream
signal pathways to induce inflammatory response and contribute to the pathology of many …

Innate immunity represents the first line of host defense against extracellular infections.
Timely initiation of inflammatory responses to invading pathogens confers host the ability to …

Abstract TRAF3 interacting protein 2 (TRAF3IP2) is important for immune responses to
pathogens, inflammatory signals and autoimmunity in mammals. In the present study, we …