A review of Sarcoptes scabiei: past, present and future

LG Arlian, MS Morgan - Parasites & vectors, 2017 - Springer
The disease scabies is one of the earliest diseases of humans for which the cause was
known. It is caused by the mite, Sarcoptes scabiei, that burrows in the epidermis of the skin …

The immunology of susceptibility and resistance to scabies

SF Walton - Parasite Immunology, 2010 - Wiley Online Library
The transmission of scabies occurs with the burrowing of Sarcoptes scabiei var. hominis
mites into the skin. Infestation invariably leads to the development of localized cutaneous …

Increased Allergic Immune Response to Sarcoptes scabiei Antigens in Crusted versus Ordinary Scabies

SF Walton, S Pizzutto, A Slender, L Viberg… - Clinical and Vaccine …, 2010 - Am Soc Microbiol
Scabies, a parasitic skin infestation by the burrowing “itch” mite Sarcoptes scabiei, causes
significant health problems for children and adults worldwide. Crusted scabies is a …

Scabies mite inactivated serine protease paralogs inhibit the human complement system

FC Bergstrom, S Reynolds, M Johnstone… - The Journal of …, 2009 - journals.aai.org
Infestation of skin by the parasitic itch mite Sarcoptes scabiei afflicts 300 million people
worldwide and there is a need for novel and efficient therapies. We have previously …

Complement inhibitors from scabies mites promote streptococcal growth–a novel mechanism in infected epidermis?

A Mika, SL Reynolds, D Pickering… - PLoS neglected …, 2012 - journals.plos.org
Background Scabies is highly prevalent in socially disadvantaged communities such as
indigenous populations and in developing countries. Generalized itching causes discomfort …

A tractable experimental model for study of human and animal scabies

K Mounsey, MF Ho, A Kelly, C Willis… - PLoS neglected …, 2010 - journals.plos.org
Background Scabies is a parasitic skin infestation caused by the burrowing mite Sarcoptes
scabiei. It is common worldwide and spreads rapidly under crowded conditions, such as …

Novel scabies mite serpins inhibit the three pathways of the human complement system

A Mika, SL Reynolds, FC Mohlin, C Willis, PM Swe… - PLoS …, 2012 - journals.plos.org
Scabies is a parasitic infestation of the skin by the mite Sarcoptes scabiei that causes
significant morbidity worldwide, in particular within socially disadvantaged populations. In …

Cathepsin B proteases of flukes: the key to facilitating parasite control?

PM Smooker, R Jayaraj, RN Pike, TW Spithill - Trends in parasitology, 2010 - cell.com
Cysteine proteases are important virulence factors for parasites. This review will focus on the
cathepsin B proteases of trematodes (also known as flukes) which are abundant in juvenile …

Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway

SL Reynolds, RN Pike, A Mika, AM Blom… - PLoS neglected …, 2014 - journals.plos.org
Scabies is an infectious skin disease caused by the mite Sarcoptes scabiei and has been
classified as one of the six most prevalent epidermal parasitic skin diseases infecting …

Parasitic mites of medical and veterinary importance–is there a common research agenda?

K Fischer, S Walton - International journal for parasitology, 2014 - Elsevier
Abstract There are an estimated 0.5–1 million mite species on earth. Among the many mites
that are known to affect humans and animals, only a subset are parasitic but these can …