Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin …
The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The …
coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The …
[HTML][HTML] Morin hydrate: A comprehensive review on novel natural dietary bioactive compound with versatile biological and pharmacological potential
SA Rajput, X Wang, HC Yan - Biomedicine & pharmacotherapy, 2021 - Elsevier
Flavonoids are natural plant-derived dietary bioactive compounds having a substantial
impact on human health. Morin hydrate is a bioflavonoid mainly obtained from fruits, stem …
impact on human health. Morin hydrate is a bioflavonoid mainly obtained from fruits, stem …
Protective effects of morin against acrylamide-induced hepatotoxicity and nephrotoxicity: A multi-biomarker approach
Acrylamide (ACR) is a heat-induced carcinogen substance that is found in some foods due
to cooking or other thermal processes. The aim of present study was to assess the probable …
to cooking or other thermal processes. The aim of present study was to assess the probable …
[HTML][HTML] Flavonoids on diabetic nephropathy: advances and therapeutic opportunities
Q Hu, C Qu, X Xiao, W Zhang, Y Jiang, Z Wu, D Song… - Chinese medicine, 2021 - Springer
With the advances in biomedical technologies, natural products have attracted substantial
public attention in the area of drug discovery. Flavonoids are a class of active natural …
public attention in the area of drug discovery. Flavonoids are a class of active natural …
Hesperidin protects against the chlorpyrifos‐induced chronic hepato‐renal toxicity in rats associated with oxidative stress, inflammation, apoptosis, autophagy, and up …
In this study, we investigated the effects of hesperidin (HSP) on oxidants/antioxidants status,
inflammation, apoptotic, and autophagic activity in hepato‐renal toxicity induced by chronic …
inflammation, apoptotic, and autophagic activity in hepato‐renal toxicity induced by chronic …
Protective effect of chrysin on cyclophosphamide-induced hepatotoxicity and nephrotoxicity via the inhibition of oxidative stress, inflammation, and apoptosis
Cyclophosphamide (CYP) is a chemotherapeutic agent used in the treatment of autoimmune
disorders and malignant diseases. However, its usage is restricted due to its severe side …
disorders and malignant diseases. However, its usage is restricted due to its severe side …
Morin attenuates acrylamide-induced testicular toxicity in rats by regulating the NF-κB, Bax/Bcl-2 and PI3K/Akt/mTOR signaling pathways
Aim Acrylamide (AC) is a carcinogenic substance which is formed during the heating of
starchy foods at high temperatures and constitutes an important risk for human health …
starchy foods at high temperatures and constitutes an important risk for human health …
Protective effects of curcumin against paclitaxel-induced spinal cord and sciatic nerve injuries in rats
Paclitaxel (PTX) is an antineoplastic agent commonly used in the treatment of solid tumors
and is known to cause dose-limiting peripheral neurotoxicity. This study was performed to …
and is known to cause dose-limiting peripheral neurotoxicity. This study was performed to …
Morin attenuates ifosfamide-induced neurotoxicity in rats via suppression of oxidative stress, neuroinflammation and neuronal apoptosis
Ifosfamide (IFA), a commonly used chemotherapeutic drug, has been frequently associated
with encephalopathy and central nervous system toxicity. The present study aims to …
with encephalopathy and central nervous system toxicity. The present study aims to …
Silymarin alleviates docetaxel-induced central and peripheral neurotoxicity by reducing oxidative stress, inflammation and apoptosis in rats
Docetaxel (DTX) is a chemotherapeutic agent used in the treatment of various malignancies
but is often associated with central and peripheral neurotoxicity. The aim of this study was to …
but is often associated with central and peripheral neurotoxicity. The aim of this study was to …