Currently becoming widely recognized, personalized psychiatry focuses on unique
physiological and genetic profiles of patients to best tailor their therapy. However, the role of …

Parkinson's disease is a common neurodegenerative disorder leading to severe disability.
The clinical features reflect progressive neuronal loss, especially involving the dopaminergic …

In this systematic review, we highlight the differences between the male and female
zebrafish brains to understand their differentiation and their use in studying sex-specific …

Epidemiological data and interventional studies with hormone replacement therapy suggest
that women, at least until menopause, are at decreased cardiovascular risk compared to …

Abstract The transcriptomic Point of Departure (tPOD) is increasingly used in ecotoxicology
to derive quantitative endpoints from RNA sequencing studies. Utilizing transcriptomic data …

Brain sex differentiation is a complex process, wherein genes and steroid hormones act to
induce specific gender brain differentiation. Testosterone (T) derived from the gonads has …

Atheriniform fishes have recently emerged as attractive models for evolutionary, ecological,
and molecular/physiological studies on sex determination. Many species in this group have …

As a synthetic androgen, 17α‐methyltestosterone (MT) is widely used in aquaculture to
induce sex reversal and may pose a potential risk to aquatic organisms. This ecological risk …

Appetite and reproduction are closely related functions that are both regulated by brain
hormones. Appetite stimulators include orexin and neuropeptide Y (NPY), and reproductive …

Members of the FOS protein family regulate gene expression responses to a multitude of
extracellular signals and are dysregulated in several pathological states. Whilst mouse …