The tridimensional (3D) organization of mammalian genomes combines structures from
different length scales. Within this organization, Topologically Associating Domains (TADs) …

Structural maintenance of chromosomes (SMC) complexes are essential proteins found in
genomes of all cellular organisms. Essential functions of these proteins, such as mitotic …

The zebrafish (Danio rerio) has been widely used in the study of human disease and
development, and about 70% of the protein-coding genes are conserved between the two …

The organization of chromatin into self-interacting domains is universal among eukaryotic
genomes, though how and why they form varies considerably. Here we report a …

Chicken erythrocytes are nucleated cells often considered to be transcriptionally inactive,
although the epigenetic changes and chromatin remodeling that would mediate …

Background Comparative genomics studies are central in identifying the coding and non-
coding elements associated with complex traits, and the functional annotation of genomes is …

Background The three-dimensional (3D) architecture of the genome has a highly ordered
and hierarchical nature, which influences the regulation of essential nuclear processes at …

Folliculogenesis is a complex biological process involving a central oocyte and its
surrounding somatic cells. Three-dimensional chromatin architecture is an important …

Studying the similarities and differences in genomic interactions between species provides
fertile grounds for determining the evolutionary dynamics underpinning genome function …

With more than 70,000 living species, vertebrates have a huge impact on the field of biology
and research, including karyotype evolution. One prominent aspect of many vertebrate …