Endometriosis is a chronic systemic disease: clinical challenges and novel innovations

HS Taylor, AM Kotlyar, VA Flores - The Lancet, 2021 - thelancet.com
Endometriosis is a common disease affecting 5–10% of women of reproductive age globally.
However, despite its prevalence, diagnosis is typically delayed by years, misdiagnosis is …

Endometriosis with infertility: A comprehensive review on the role of immune deregulation and immunomodulation therapy

K Kolanska, J Alijotas‐Reig, J Cohen… - American Journal of …, 2021 - Wiley Online Library
Background Endometriosis is a multifactorial pathology dependent on intrinsic and extrinsic
factors, but the immune deregulation seems to play a pivotal role. In endometriosis …

Gut microbiota exceeds cervical microbiota for early diagnosis of endometriosis

L Huang, B Liu, Z Liu, W Feng, M Liu… - Frontiers in cellular …, 2021 - frontiersin.org
The diagnosis of endometriosis is typically delayed by years for the unexclusive symptom
and the traumatic diagnostic method. Several studies have demonstrated that gut microbiota …

[HTML][HTML] Endometriosis-associated ovarian carcinomas: Insights into pathogenesis, diagnostics, and therapeutic targets—A narrative review

EP Samartzis, SI Labidi-Galy, M Moschetta… - Annals of …, 2020 - ncbi.nlm.nih.gov
Endometriosis is a benign gynecologic condition affecting up to one woman out of ten of
reproductive age. It is defined by the presence of endometrial-like tissue in localizations …

Transcriptome meta-analysis reveals differences of immune profile between eutopic endometrium from stage I-II and III-IV endometriosis independently of hormonal …

OB Poli-Neto, J Meola, JC Rosa-e-Silva, D Tiezzi - Scientific Reports, 2020 - nature.com
Eutopic endometrium appears to be crucial for endometriosis development. Despite of the
evident importance, data regarding the cellular microenvironment remain unclear. Our …

Diagnostic significance of selected serum inflammatory markers in women with advanced endometriosis

I Kokot, A Piwowar, M Jędryka, K Sołkiewicz… - International journal of …, 2021 - mdpi.com
Endometriosis is a gynecological disease, the pathogenesis of which seems to be directly
associated with inflammatory processes. Serum concentrations of IL-1β, IL-6, hs-CRP, IgG …

[HTML][HTML] Emerging hallmarks of endometriosis metabolism: a promising target for the treatment of endometriosis

J Lu, X Ling, L Liu, A Jiang, C Ren, C Lu… - Biochimica et Biophysica …, 2023 - Elsevier
Endometriosis, characterized by ectopic endometrium growth in the extrauterine
environment, is one of the most notable diseases of the female reproductive system …

New biomarkers in endometriosis

LM Coutinho, MC Ferreira, ALL Rocha… - Advances in clinical …, 2019 - Elsevier
Endometriosis is a benign gynecological disorder which presents significant challenges in
terms of diagnosis and management. Despite decades of research, there are no sufficiently …

The vaginal microbiome as a tool to predict rASRM stage of disease in endometriosis: a pilot study

AR Perrotta, GM Borrelli, CO Martins, EG Kallas… - Reproductive …, 2020 - Springer
Endometriosis remains a challenge to understand and to diagnose. This is an observational
cross-sectional pilot study to characterize the gut and vaginal microbiome profiles among …

Metabolic profile of patients with severe endometriosis: a prospective experimental study

F Murgia, S Angioni, MN D'Alterio, S Pirarba… - Reproductive …, 2021 - Springer
Endometriosis is a common disease affecting women in reproductive age. There are several
hypotheses on the pathogenesis of this disease. Often, its lesions and symptoms overlap …