Neurodevelopmental disorders (NDDs), including intellectual disability (ID) and autism
spectrum disorders (ASD), are a large group of disorders in which early insults during brain …

During embryonic brain development, neural progenitor/stem cells (NPCs) sequentially give
rise to different subtypes of neurons and glia via a highly orchestrated process. To …

Neural stem cells (NSCs) have the ability to self-renew and give rise to neurons and glial
cells (astrocytes and oligodendrocytes) in the mammalian central nervous system. This …

Epigenetically regulated transcriptional plasticity has been proposed as a mechanism of
differentiation arrest and resistance to therapy. BCR-ABL leukemias result from leukemic …

Abstract Omega-3 (n-3) fatty acids modulate epigenetic changes critical to genesis and
differentiation of neural cells. Conversely, maternal protein-malnutrition can negatively …

Suberoylanilide hydroxamic acid (SAHA) has been reported preclinically to diffuse across
the placenta and to be found in fetal plasma, sugges ng that it can influence the fetus if taken …

In the mammalian brain, neuronal networks are supported by glial cells. All of the neural cell
types, ie, neurons, astrocytes and oligodendrocytes, are generated from neural stem cells …