Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

[HTML][HTML] Clinical characteristics, surveillance, treatment allocation, and outcomes of non-alcoholic fatty liver disease-related hepatocellular carcinoma: a systematic …

DJH Tan, CH Ng, SY Lin, XH Pan, P Tay… - The Lancet …, 2022 - thelancet.com
Background The clinical presentation and outcomes of non-alcoholic fatty liver disease
(NAFLD)-related hepatocellular carcinoma are unclear when compared with hepatocellular …

Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer

DQ Huang, AG Singal, Y Kono, DJH Tan, HB El-Serag… - Cell metabolism, 2022 - cell.com
Liver cancer epidemiology is changing due to increasing alcohol consumption, rising
prevalence of obesity, and advances in hepatitis B virus (HBV) and hepatitis C virus (HCV) …

Global burden of liver cancer in males and females: changing etiological basis and the growing contribution of NASH

DJH Tan, VW Setiawan, CH Ng, WH Lim… - Hepatology, 2023 - journals.lww.com
Global burden of liver cancer in males and females: Changing... : Hepatology Global burden of
liver cancer in males and females: Changing etiological basis and the growing contribution of …

Nonalcoholic fatty liver disease and hepatocellular carcinoma: Insights in epidemiology, pathogenesis, imaging, prevention and therapy

SA Polyzos, L Chrysavgis, ID Vachliotis… - Seminars in cancer …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is estimated to be the third leading cause of cancer-related
mortality and is characterized by low survival rates. Nonalcoholic fatty liver disease (NAFLD) …

Multicenter validation of abbreviated MRI for detecting early-stage hepatocellular carcinoma

T Yokoo, N Masaki, ND Parikh, BF Lane, Z Feng… - Radiology, 2023 - pubs.rsna.org
Background Abbreviated MRI is a proposed paradigm shift for hepatocellular carcinoma
(HCC) surveillance, but data on its performance are lacking for histopathologically confirmed …

[HTML][HTML] Nonalcoholic fatty liver disease versus metabolic-associated fatty liver disease: Prevalence, outcomes and implications of a change in name

CH Ng, DQ Huang, MH Nguyen - Clinical and Molecular …, 2022 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) affects about a third of the world's adult population
and is a major public health concern. NAFLD is defined by the presence of hepatic steatosis …

Shared mechanisms between cardiovascular disease and NAFLD

DQ Huang, M Downes, RM Evans… - Seminars in liver …, 2022 - thieme-connect.com
The burden of nonalcoholic fatty liver disease (NAFLD) is rising globally. Cardiovascular
disease is the leading cause of death in patients with NAFLD. Nearly half of individuals with …

the role of HSD17B13 on global epidemiology, natural history, pathogenesis and treatment of NAFLD

M Amangurbanova, DQ Huang… - Alimentary …, 2023 - Wiley Online Library
Background Non‐alcoholic fatty liver disease (NAFLD) occurs in around a quarter of the
global population and is one of the leading causes of chronic liver disease. The phenotypic …

Clinical utility of combined MRI-PDFF and ALT response in predicting histologic response in nonalcoholic fatty liver disease

DQ Huang, SR Sharpton… - Clinical …, 2023 - cghjournal.org
Methods This longitudinal prospective study included 108 consecutive well-phenotyped
patients (61% women) with biopsy-proven NAFLD who underwent detailed standardized …