Long-read human genome sequencing and its applications

GA Logsdon, MR Vollger, EE Eichler - Nature Reviews Genetics, 2020 - nature.com
Over the past decade, long-read, single-molecule DNA sequencing technologies have
emerged as powerful players in genomics. With the ability to generate reads tens to …

Next generation sequencing of SARS-CoV-2 genomes: challenges, applications and opportunities

M Chiara, AM D'Erchia, C Gissi… - Briefings in …, 2021 - academic.oup.com
Various next generation sequencing (NGS) based strategies have been successfully used in
the recent past for tracing origins and understanding the evolution of infectious agents …

[HTML][HTML] COVID-19 and Bangladesh: challenges and how to address them

S Anwar, M Nasrullah, MJ Hosen - Frontiers in public health, 2020 - frontiersin.org
As the coronavirus outbreak quickly surges worldwide, many countries are adopting non-
therapeutic preventive measures, which include travel bans, remote office activities, country …

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

JFW Chan, S Yuan, KH Kok, KKW To, H Chu, J Yang… - The lancet, 2020 - thelancet.com
Background An ongoing outbreak of pneumonia associated with a novel coronavirus was
reported in Wuhan city, Hubei province, China. Affected patients were geographically linked …

[HTML][HTML] Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

KA Ryan, KR Bewley, SA Fotheringham… - Nature …, 2021 - nature.com
There is a vital need for authentic COVID-19 animal models to enable the pre-clinical
evaluation of candidate vaccines and therapeutics. Here we report a dose titration study of …

Nanopore targeted sequencing for the accurate and comprehensive detection of SARS‐CoV‐2 and other respiratory viruses

M Wang, A Fu, B Hu, Y Tong, R Liu, Z Liu, J Gu… - Small, 2020 - Wiley Online Library
The ongoing global novel coronavirus pneumonia COVID‐19 outbreak has engendered
numerous cases of infection and death. COVID‐19 diagnosis relies upon nucleic acid …

[HTML][HTML] Biosensors: frontiers in rapid detection of COVID-19

R Samson, GR Navale, MS Dharne - 3 Biotech, 2020 - Springer
The rapid community-spread of novel human coronavirus 2019 (nCOVID19 or SARS-Cov2)
and morbidity statistics has put forth an unprecedented urge for rapid diagnostics for quick …

The presence of SARS-CoV-2 RNA in human sewage in Santa Catarina, Brazil, November 2019

G Fongaro, PH Stoco, DSM Souza, EC Grisard… - Science of The Total …, 2021 - Elsevier
Abstract Human sewage from Florianopolis (Santa Catarina, Brazil) was analyzed for severe
acute respiratory syndrome coronavirus-2 (SARS-CoV2) from October 2019 until March …

[HTML][HTML] Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19

FJ Salguero, AD White, GS Slack… - Nature …, 2021 - nature.com
A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current
COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to …

Agnostic sequencing for detection of viral pathogens

NPG Gauthier, SD Chorlton, M Krajden… - Clinical microbiology …, 2023 - Am Soc Microbiol
The advent of next-generation sequencing (NGS) technologies has expanded our ability to
detect and analyze microbial genomes and has yielded novel molecular approaches for …