Suberosin alleviates thiazolidinedione-induced cardiomyopathy in diabetic rats by inhibiting ferroptosis via modulation of ACSL4-LPCAT3 and PI3K-AKT signaling …

S Iqbal, F Jabeen, I Kahwa, T Omara - Cardiovascular Toxicology, 2023 - Springer
Thiazolidinediones are useful antidiabetic medications. However, their use is associated
with adverse side effects like edema, heart failure and bone fractures. In this study, we …

A review of the ethnomedicinal, phytochemical, and pharmacological properties of the Ferulago genus based on Structure–Activity Relationship (SAR) of coumarins

F Dabaghian, S Aalinezhad, AR Kesheh… - DARU Journal of …, 2024 - Springer
Abstract Background The Ferluago WDJ Koch genus includes 48 accepted perennial herbs
that are distributed in the Mediterranean region, Southeast Europe, Central and Middle East …

Ubiquitin-specific peptidase 47 (USP47) regulates cutaneous oxidative injury through nicotinamide nucleotide transhydrogenase (NNT)

X Li, K Qian, Y Zhang, Y Zhang, Y Liu, C Sun… - Toxicology and Applied …, 2023 - Elsevier
Human skin is daily exposed to oxidative stresses in the environment such as physical
stimulation, chemical pollutants and pathogenic microorganisms, which are likely to cause …

[HTML][HTML] Aquaporins: Potential Targets in Inflammatory Diseases

A Bozkurt, H Halici, M Yayla - The Eurasian Journal of Medicine, 2023 - ncbi.nlm.nih.gov
Inflammation involves a long chain of molecular reactions and cellular activity designed to
repair tissue damaged by various causes. The inflammatory process and its complex …

[HTML][HTML] Experimental Sepsis Models: Advantages and Limitations

P Aydın, H Bekmez - The Eurasian Journal of Medicine, 2023 - ncbi.nlm.nih.gov
Sepsis is a major health problem that causes millions of deaths worldwide every year. Due
to the complexity of its pathophysiology, there is no clear treatment method for it. Existing …

Identification of potential biomarkers for sepsis based on neutrophil extracellular trap-related genes

J Tang, H Lu, Z Xie, X Jia, T Su, B Lin - Diagnostic Microbiology and …, 2024 - Elsevier
Sepsis is a highly lethal disease that poses a serious threat to human health. Increasing
evidence indicates that neutrophil extracellular traps (NETs) are key factors in the …

[HTML][HTML] Benefits of Some Phytochemical Compounds in Experimental Sepsis Models: A Therapeutic Perspective

B Ozdemir, P Bayram, SA Karamese - The Eurasian Journal of …, 2023 - ncbi.nlm.nih.gov
Sepsis represents a major contributor to mortality among critically ill patients, imposing a
substantial economic strain on health-care systems. The uncontrolled inflammatory …

The protective effect of dexmedetomidine on the liver injury in sepsis through inhibition of necroptosis

Y Meng, S Meng, Y Zhang, Y Song, E Wang, G Wang… - Shock, 2023 - journals.lww.com
Background Sepsis-induced liver injury leads to extensive necroptosis in hepatocytes, which
is the main factor of liver dysfunction. This study aims to investigate the protective effect of …

Antifungal Activity of Extracts From the Ferulago Pauciradiata in Vitro Against Botrytis Cinerea Pers

S Karakuş, TN Suyurdu, E Köksal… - Journal of the Institute of …, 2023 - dergipark.org.tr
This is the first study to reveal the antifungal properties of Ferulago pauciradiata plant. In this
context investigated the effects of methanol (FPM), ethanol (FPE), hexane (FPH) and water …