Non-spherical micro-and nanoparticles for drug delivery: Progress over 15 years

N Kapate, JR Clegg, S Mitragotri - Advanced Drug Delivery Reviews, 2021 - Elsevier
Shape of particulate drug carries has been identified as a key parameter in determining their
biological outcome. In this review, we analyze the field of particle shape as it shifts from …

Biocompatible anisotropic polymeric particles: synthesis, characterization, and biomedical applications

I Mirza, S Saha - ACS Applied Bio Materials, 2020 - ACS Publications
Recently, biocompatible anisotropic particles have emerged as a powerful platform in the
biomedical field, especially in the areas such as therapeutics, theranostics, biosensor …

Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal

E Ben-Akiva, RA Meyer, H Yu, JT Smith, DM Pardoll… - Science …, 2020 - science.org
The design of next-generation nanobiomaterials requires precise engineering of both
physical properties of the core material and chemical properties of the material's surface to …

Microfluidic study of retention and elimination of abnormal red blood cells by human spleen with implications for sickle cell disease

Y Qiang, A Sissoko, ZL Liu, T Dong… - Proceedings of the …, 2023 - National Acad Sciences
The spleen clears altered red blood cells (RBCs) from circulation, contributing to the balance
between RBC formation (erythropoiesis) and removal. The splenic RBC retention and …

Features of Anisotropic Drug Delivery Systems

V Kudryavtseva, GB Sukhorukov - Advanced Materials, 2024 - Wiley Online Library
Natural materials are anisotropic. Delivery systems occurring in nature, such as viruses,
blood cells, pollen, and many others, do have anisotropy, while delivery systems made …

Fabrication of amine‐decorated nonspherical microparticles with calcium peroxide cargo for controlled release of oxygen

S Khorshidi, A Karkhaneh… - Journal of Biomedical …, 2020 - Wiley Online Library
Oxygen is an important signaling molecule which affects many behaviors of bone progenitor
cells. Oxygen releasing biomaterials depend on their material and design are able to …

Role of particle shape on efficient and organ-based drug delivery

S Nejati, EM Vadeghani, S Khorshidi… - European Polymer …, 2020 - Elsevier
Encapsulation of drugs in nano-and microparticles has been known as a promising
approach for efficient drug delivery. It has been well established that adjusting the …

Particle-Based Artificial Antigen-Presenting Cell Systems for T Cell Activation in Adoptive T Cell Therapy

F Hou, Z Guo, MT Ho, Y Hui, CX Zhao - ACS nano, 2024 - ACS Publications
T cell-based adoptive cell therapy (ACT) has emerged as a promising treatment for various
diseases, particularly cancers. Unlike other immunotherapy modalities, ACT involves directly …

Leveraging biomaterials for enhancing T cell immunotherapy

Z Liao, W Zhang, H Zheng, Y Wang, J Yu, H Li… - Journal of Controlled …, 2022 - Elsevier
The dynamic roles of T cells in the immune system to recognize and destroy the infected or
mutated cells render T cell therapy a prospective treatment for a variety of diseases …

Advances in functionalization of bioresorbable nanomembranes and nanoparticles for their use in biomedicine

AHM Mohammed-Sadhakathullah… - International Journal of …, 2023 - mdpi.com
Bioresorbable nanomembranes (NMs) and nanoparticles (NPs) are powerful polymeric
materials playing an important role in biomedicine, as they can effectively reduce infections …