Benzimidazole, the benzo derivative of imidazole, is a class of bicyclic aromatic organic
compound consisting of six‐membered benzene ring fused to five‐membered imidazole at 4 …

Cancer, characterized by a deregulation of the cell cycle which mainly results in a
progressive loss of cellular differentiation and uncontrolled cellular growth, remains a …

Targeted therapy plays a pivotal role in cancer therapeutics by countering the drawbacks of
conventional treatment like adverse events and drug resistance. Over the last decade …

Abstract 3D cell cultures are becoming the new standard for cell-based in vitro research, due
to their higher transferrability toward in vivo biology. The lack of established techniques for …

We designed and synthesized a series of symmetric bis-6-amidino-benzothiazole
derivatives with aliphatic central units and evaluated their efficacy against bloodstream …

In the present study, a series of 2-phenyl-1H-benzo [d] imidazole-based α-glucosidase
inhibitors were synthesized and evaluated for their in vitro and in vivo anti-diabetic potential …

Herein we present the design and the synthesis of novel substituted coumarin–
benzimidazole/benzothiazole hybrids bearing a cyclic amidino group on the benzazole core …

A series of benzothiazole based dispersed azo compounds were synthesized by
diazotization of benzothiazole derivatives coupling with antipyrine through traditional …

A series of 6-amidinobenzothiazoles, linked via phenoxymethylene or directly to the 1, 2, 3-
triazole ring with ap-substituted phenyl or benzyl moiety, were synthesised and evaluated in …

As a result of our previous research focussed on benzimidazoles, herein we present design,
synthesis, QSAR analysis and biological activity of novel N-substituted benzimidazole …