The last malaria parasite standing will display effective adaptations to selective forces. While
substantial progress has been made in reducing malaria mortality, eradication will require …

Malaria elimination means cessation of parasite transmission. At present, the declining
malaria incidence in many countries has made elimination a feasible goal. Transmission …

Background Understanding the human malaria infectious reservoir is important for
elimination initiatives. Here, we implemented mosquito membrane feeding experiments to …

Plasmodium transmission from humans to mosquitoes is an understudied bottleneck in the
transmission of malaria. Direct membrane feeding assays (DMFA) allow detailed malaria …

Despite many advances in medicine, Plasmodium falciparum malaria remains a major
public health threat in sub-Saharan Africa, where it kills one child every minute. While there …

Long regulatory elements (LREs), such as CpG islands, polydA: dT tracts or AU-rich
elements, are thought to play key roles in gene regulation but, as opposed to conventional …

Abstract While the sub-Saharan African region carries a disproportionately high amount of
the global malaria burden, many historically endemic areas are moving towards elimination …

A promising strategy to achieve malaria elimination is by interrupting transmission using
transmission-blocking vaccines (TBVs). TBVs target the sexual or mosquito stages of the …