Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies

MA Waszczuk, KG Jonas, M Bornovalova, G Breen… - Molecular …, 2023 - nature.com
Genome-wide association studies (GWAS) provide biological insights into disease onset
and progression and have potential to produce clinically useful biomarkers. A growing body …

Shedding light on antisocial behavior through genetically informed research

P Pezzoli, EJ McCrory, E Viding - Annual Review of Psychology, 2024 - annualreviews.org
Antisocial behavior (ASB) refers to a set of behaviors that violate social norms and disregard
the well-being and rights of others. In this review, we synthesize evidence from studies using …

A genetically informed Registered Report on adverse childhood experiences and mental health

JR Baldwin, HM Sallis, T Schoeler, MJ Taylor… - Nature human …, 2023 - nature.com
Children who experience adversities have an elevated risk of mental health problems.
However, the extent to which adverse childhood experiences (ACEs) cause mental health …

An 'embedded brain'approach to understanding antisocial behaviour

E Viding, E McCrory, A Baskin-Sommers… - Trends in Cognitive …, 2024 - cell.com
Antisocial behaviour (ASB) incurs substantial costs to the individual and society. Cognitive
neuroscience has the potential to shed light on developmental risk for ASB, but it cannot …

Reciprocal effects between negative parenting and children's callous-unemotional traits from mid to late childhood

P Pezzoli, JB Pingault, M Malanchini… - American Journal of …, 2024 - Am Psychiatric Assoc
Objective: The role of negative parenting in the development of callous-unemotional (CU)
traits remains unclear. Both negative parenting and CU traits are influenced by genetic and …

Update on Antisocial Personality Disorder

DW Black - Current Psychiatry Reports, 2024 - Springer
Abstract Purpose of Review Antisocial personality disorder (ASPD) is a characterized by
lifelong or recurrent behavioral problems that begin in childhood or early adolescence. This …

Human nature and personality variation: Reconnecting evolutionary psychology with the science of individual differences

D Maestripieri, BB Boutwell - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
The scientific study of human behavior from a modern evolutionary perspective began in the
20th century with disciplines such as human ethology and behavioral ecology as well as …

Investigating genetically stratified subgroups to better understand the etiology of alcohol misuse

AB Thijssen… - Molecular …, 2023 - nature.com
Alcohol misuse (AM) is highly prevalent and harmful, with theorized subgroups differing on
internalizing and externalizing dimensions. Despite known heterogeneity, genome-wide …

Schizophrenia mediating the effect of smoking phenotypes on antisocial behavior: A Mendelian randomization analysis

M Zhang, J Tang, W Li, K Xue, Z Wang… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims Previous studies have indicated that smoking is linked to an increased risk of
developing schizophrenia, and that individuals with schizophrenia are more prone to …

The shared genetic etiology of antisocial behavior and psychiatric disorders: Insights from pleiotropy and causality analysis

S Wang, YL Dan, Y Yang, Y Tian - Journal of Affective Disorders, 2024 - Elsevier
Background Antisocial behavior (ASB) infringes on the rights of others and significantly
disrupts social order. Studies have shown that ASB is phenotypically associated with various …