The budding yeast Saccharomyces cerevisiae has been the principal organism used in
experiments to examine genetic recombination in eukaryotes. Studies over the past decade …

Homologous recombination is essential during meiosis in most sexually reproducing
organisms. In budding yeast, and most likely in other organisms as well, meiotic …

Meiotic recombination is carried out through a specialized pathway for the formation and
repair of DNA double-strand breaks made by the Spo11 protein, a relative of archaeal …

We report here that the apoptosis-promoting protein TIA-1 regulates alternative pre-mRNA
splicing of the Drosophila melanogaster gene male-specific-lethal 2 and of the human …

In Saccharomyces cerevisiae, Mre11 protein is involved in both double‐strand DNA break
(DSB) repair and meiotic DSB formation. Here, we report the correlation of nuclease and …

Splicing of the K-SAM alternative exon of the fibroblast growth factor receptor 2 gene is
heavily dependent on the U-rich sequence IAS1 lying immediately downstream from its 5 …

DNA helicases are found in all kingdoms of life and function in all DNA metabolic processes
where the two strands of duplex DNA require to be separated. Here, we review recent …

Crossover recombination is essential for homolog segregation during meiosis. In contrast to
spontaneous mitotic recombination, meiotic recombination is intrinsic being initiated by the …

The MER3 gene is identified as a novel meiosis‐specific gene, whose transcript is spliced in
an MRE2/MER1‐dependent manner. The predicted Mer3 protein contains the seven motifs …

The U1 snRNP is essential for recognition of the pre-mRNA 5′-splice site and the
subsequent assembly of the spliceosome. Yeast U1 snRNP is considerably more complex …