A guide to time‐resolved structural analysis of light‐activated proteins

H Poddar, DJ Heyes, G Schirò, M Weik… - The FEBS …, 2022 - Wiley Online Library
Dynamical changes in protein structures are essential for protein function and occur over
femtoseconds to seconds timescales. X‐ray free electron lasers have facilitated …

Tips and turns of bacteriophytochrome photoactivation

H Takala, P Edlund, JA Ihalainen… - Photochemical & …, 2020 - pubs.rsc.org
Phytochromes are ubiquitous photosensor proteins, which control the growth, reproduction
and movement in plants, fungi and bacteria. Phytochromes switch between two …

Protein control of photochemistry and transient intermediates in phytochromes

G Salvadori, V Macaluso, G Pellicci, L Cupellini… - Nature …, 2022 - nature.com
Phytochromes are ubiquitous photoreceptors responsible for sensing light in plants, fungi
and bacteria. Their photoactivation is initiated by the photoisomerization of the embedded …

Individual and shared digital repertoires–older adults managing digital services

R Hänninen, L Pajula, V Korpela… - … Communication & Society, 2023 - Taylor & Francis
The rise of public and other non-recreational digital services is based on the idea of catering
to the daily needs of the citizens cost-efficiently and with ease. Previous research has …

Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component signaling

E Multamäki, R Nanekar, D Morozov… - Nature …, 2021 - nature.com
Bacterial phytochrome photoreceptors usually belong to two-component signaling systems
which transmit environmental stimuli to a response regulator through a histidine kinase …

Photoreception and signaling in bacterial phytochrome revealed by single-particle cryo-EM

TN Malla, C Hernandez, S Muniyappan… - Science …, 2024 - science.org
Phytochromes are red-light photoreceptors discovered in plants with homologs in bacteria
and fungi that regulate a variety of physiological responses. They display a reversible …

Vibrational couplings between protein and cofactor in bacterial phytochrome Agp1 revealed by 2D-IR spectroscopy

D Buhrke, N Michael, P Hamm - Proceedings of the …, 2022 - National Acad Sciences
Phytochromes are ubiquitous photoreceptor proteins that undergo a significant refolding of
secondary structure in response to initial photoisomerization of the chromophoric group …

Chromophore–protein interplay during the phytochrome photocycle revealed by step-scan FTIR spectroscopy

JA Ihalainen, E Gustavsson, L Schroeder… - Journal of the …, 2018 - ACS Publications
Phytochrome proteins regulate many photoresponses of plants and microorganisms. Light
absorption causes isomerization of the biliverdin chromophore, which triggers a series of …

Bacteriophytochromes–from informative model systems of phytochrome function to powerful tools in cell biology

G Gourinchas, S Etzl, A Winkler - Current opinion in structural biology, 2019 - Elsevier
Highlights•Fluorescent probes or optogenetic tools can be developed using phytochrome
modules.•Bacteriophytochromes provide advantageous properties in protein engineering …

On the (un) coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome

H Takala, HK Lehtivuori, O Berntsson, A Hughes… - Journal of Biological …, 2018 - ASBMB
Phytochromes are photoreceptors in plants, fungi, and various microorganisms and cycle
between metastable red light–absorbing (Pr) and far-red light–absorbing (Pfr) states. Their …