In addition to immediate implications for pregnancy complications, increasing evidence
implicates maternal obesity as a major determinant of offspring health during childhood and …

The fact that not all individuals exposed to the same environmental risk factors develop
obesity supports the hypothesis of the existence of underlying genetic and epigenetic …

Background: Characterization of the epigenome is a primary interest for children's
environmental health researchers studying the environmental influences on human …

Over the last few decades, the prevalence of obesity has risen to epidemic proportions
worldwide. Consequently, the number of obesity in pregnancy has risen drastically …

Background: Evidence suggests that in utero exposure to undernutrition and overnutrition
might affect adiposity in later life. Epigenetic modification is suggested as a plausible …

Pre-pregnancy maternal obesity is associated with adverse offspring outcomes at birth and
later in life. Individual studies have shown that epigenetic modifications such as DNA …

The increased prevalence of obesity and related comorbidities is a major public health
problem. While genetic factors undoubtedly play a role in determining individual …

Study of monogenic forms of obesity has demonstrated the pivotal role of the central leptin–
melanocortin pathway in controlling energy balance, appetite and body weight. The majority …

Environmental factors can induce epigenetic alterations in the germ cells that can potentially
be transmitted transgenerationally. This non-genetic form of inheritance is termed epigenetic …

Obesity has reached epidemic proportions globally. Although modern adoption of a
sedentary lifestyle coupled with energy-dense nutrition is considered to be the main cause …