Alzheimer's disease (AD) is the most common cause of dementia, affecting the central
nervous system (CNS) through the accumulation of intraneuronal neurofibrillary tau tangles …

Biological material is one of the most important aspects that allow for the correct diagnosis of
the disease, and tears are an interesting subject of research because of the simplicity of …

Tear fluid is receiving growing attention as a source for novel diagnostic biomarkers.
Multiple techniques are available for its collection and impact the composition of acquired …

There has been increasing interest in finding non-invasive biomarkers for
neurodegenerative diseases such as Alzheimer's disease (AD). This observational study …

Neurodegeneration is a highly complex process which is associated with a variety of
molecular mechanisms related to ageing. Among neurodegenerative disorders, Alzheimer's …

MicroRNAs are non-coding RNAs that serve as regulatory molecules in a variety of
pathways such as inflammation, metabolism, homeostasis, cell machinery, and …

The change from viewing noncoding RNA as “junk” in the genome to seeing it as a critical
epigenetic regulator in almost every human condition or disease has forced a paradigm shift …

Proteomics and metabolomics are two emerging fields that hold promise to shine light on the
molecular mechanisms causing neurodegenerative diseases. Research in this area may …

Background: Alzheimer's (AD) and Parkinson's diseases (PD) show deposits of improperly
folded modified proteins. Protein expression mechanisms are involved since the early …

Epilepsy diagnosis is complex, requires a team of specialists and relies on in-depth patient
and family history, MRI-imaging and EEG monitoring. There is therefore an unmet clinical …