Omega-9 fatty acids: Potential roles in inflammation and cancer management

MA Farag, MZ Gad - Journal of Genetic Engineering and Biotechnology, 2022 - Elsevier
Background Omega-9 fatty acids represent one of the main mono-unsaturated fatty acids
(MUFA) found in plant and animal sources. They are synthesized endogenously in humans …

[HTML][HTML] Mechanisms of action of trans fatty acids

AB Oteng, S Kersten - Advances in nutrition, 2020 - Elsevier
Human studies have established a positive association between the intake of industrial trans
fatty acids and the development of cardiovascular diseases, leading several countries to …

Dietary fat and cancer—which is good, which is bad, and the body of evidence

B Bojková, PJ Winklewski… - International journal of …, 2020 - mdpi.com
A high-fat diet (HFD) induces changes in gut microbiota leading to activation of pro-
inflammatory pathways, and obesity, as a consequence of overnutrition, exacerbates …

SARS-CoV-2 nonstructural protein 6 triggers endoplasmic reticulum stress-induced autophagy to degrade STING1

P Jiao, W Fan, X Ma, R Lin, Y Zhao, Y Li, H Zhang… - Autophagy, 2023 - Taylor & Francis
ABSTRACT SARS-CoV-2 poses a substantial global threat owing to the emergence of
several highly transmissible variants. Autophagy is an intracellular degradation process that …

In-vitro evaluation of apoptotic effect of OEO and thymol in 2D and 3D cell cultures and the study of their interaction mode with DNA

T Jamali, G Kavoosi, M Safavi, SK Ardestani - Scientific Reports, 2018 - nature.com
Oliveria decumbens is an Iranian endemic plant used extensively in traditional medicine.
Recently, some studies have been performed on biological effects of Oliveria essential oil …

Elaidic acid induced NLRP3 inflammasome activation via ERS-MAPK signaling pathways in Kupffer cells

H Liu, B Nan, C Yang, X Li, H Yan, Y Yuan - Biochimica et Biophysica Acta …, 2022 - Elsevier
Trans fatty acids (TFA) in food can cause liver inflammation. Activation of NOD-like receptor
protein-3 (NLRP3) inflammasome is a key factor in the regulation of inflammation …

Melatonin promotes apoptosis of colorectal cancer cells via superoxide-mediated ER stress by inhibiting cellular prion protein expression

CW Yun, S Kim, JH Lee, SH Lee - Anticancer research, 2018 - ar.iiarjournals.org
Background/Aim: Melatonin, an endogenously secreted indoleamine hormone that is
produced in the pineal gland, is known to possess antitumor effect via various mechanisms …

Trans-fatty acids as an enhancer of inflammation and cell death: molecular basis for their pathological actions

Y Hirata - Biological and Pharmaceutical Bulletin, 2021 - jstage.jst.go.jp
Abstract trans-Fatty acids (TFAs) are food-derived fatty acids that possess one or more trans
double bonds between carbon atoms. Compelling epidemiological and clinical evidence …

Ilimaquinone (marine sponge metabolite) induces apoptosis in HCT-116 human colorectal carcinoma cells via mitochondrial-mediated apoptosis pathway

M Surti, M Patel, A Redhwan, LA Al-Keridis, M Adnan… - Marine Drugs, 2022 - mdpi.com
Ilimaquinone (IQ), a metabolite found in marine sponges, has been reported to have a
number of biological properties, including potential anticancer activity against colon cancer …

Cis-monounsaturated fatty acids inhibit ferroptosis through downregulation of transferrin receptor 1

K Shan, G Fu, J Li, Y Qi, N Feng, Y Li, YQ Chen - Nutrition Research, 2023 - Elsevier
Ferroptosis, a form of cell death mediated by lipid peroxidation, is implicated in various
pathological processes. Although monounsaturated fatty acids (MUFAs) can inhibit …