Oxytocin, neural plasticity, and social behavior

RC Froemke, LJ Young - Annual Review of Neuroscience, 2021 - annualreviews.org
Oxytocin regulates parturition, lactation, parental nurturing, and many other social behaviors
in both sexes. The circuit mechanisms by which oxytocin modulates social behavior are …

Marmosets: a neuroscientific model of human social behavior

CT Miller, WA Freiwald, DA Leopold, JF Mitchell… - Neuron, 2016 - cell.com
The common marmoset (Callithrix jacchus) has garnered interest recently as a powerful
model for the future of neuroscience research. Much of this excitement has centered on the …

A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics

T Meira, F Leroy, EW Buss, A Oliva, J Park… - Nature …, 2018 - nature.com
Recent results suggest that social memory requires the dorsal hippocampal CA2 region as
well as a subset of ventral CA1 neurons. However, it is unclear whether dorsal CA2 and …

A circuit from hippocampal CA2 to lateral septum disinhibits social aggression

F Leroy, J Park, A Asok, DH Brann, T Meira, LM Boyle… - Nature, 2018 - nature.com
Although the hippocampus is known to be important for declarative memory, it is less clear
how hippocampal output regulates motivated behaviours, such as social aggression. Here …

A distributed network for social cognition enriched for oxytocin receptors

M Mitre, BJ Marlin, JK Schiavo, E Morina… - Journal of …, 2016 - Soc Neuroscience
Oxytocin is a neuropeptide important for social behaviors such as maternal care and parent–
infant bonding. It is believed that oxytocin receptor signaling in the brain is critical for these …

Rediscovering area CA2: unique properties and functions

SM Dudek, GM Alexander, S Farris - Nature Reviews Neuroscience, 2016 - nature.com
Hippocampal area CA2 has several features that distinguish it from CA1 and CA3, including
a unique gene expression profile, failure to display long-term potentiation and relative …

[HTML][HTML] The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation

CR Lee, A Chen, KM Tye - Cell, 2021 - cell.com
Social homeostasis is the ability of individuals to detect the quantity and quality of social
contact, compare it to an established set-point in a command center, and adjust the effort …

Hippocampal CA2 activity patterns change over time to a larger extent than between spatial contexts

EA Mankin, GW Diehl, FT Sparks, S Leutgeb… - Neuron, 2015 - cell.com
The hippocampal CA2 subregion has a different anatomical connectivity pattern within the
entorhino-hippocampal circuit than either the CA1 or CA3 subregion. Yet major differences …

Perineuronal nets suppress plasticity of excitatory synapses on CA2 pyramidal neurons

KE Carstens, ML Phillips, L Pozzo-Miller… - Journal of …, 2016 - Soc Neuroscience
Long-term potentiation of excitatory synapses on pyramidal neurons in the stratum radiatum
rarely occurs in hippocampal area CA2. Here, we present evidence that perineuronal nets …

The corticohippocampal circuit, synaptic plasticity, and memory

J Basu, SA Siegelbaum - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Synaptic plasticity serves as a cellular substrate for information storage in the central
nervous system. The entorhinal cortex (EC) and hippocampus are interconnected brain …