Molecular mechanisms of cognitive impairment associated with stroke

M Kaur, S Sharma - Metabolic brain disease, 2022 - Springer
Stroke is the second leading cause of death after coronary heart disease in developed
countries and is the greatest cause of disability and cognitive impairment. Risk factors for …

Targeting hypercoagulation to alleviate Alzheimer's disease progression in metabolic syndrome

S Khan, S Pati, S Singh, M Akhtar, P Khare… - International Journal of …, 2022 - nature.com
Abstract Introduction Metabolic Syndrome (MetS) constitutes an important risk factor for
Alzheimer's disease (AD); however, the mechanism linking these two disorders has not …

A multifunctional carbon quantum dot overcoming the BBB for modulating amyloid aggregation and scavenging reactive oxygen species

C Yan, Y Wang, Y Ma, H Liu, S Tang, Y Li, J Shi… - Materials Today …, 2024 - Elsevier
The abnormal aggregation of β-amyloid (Aβ), the accumulation of reactive oxygen species
(ROS), and the presence of the blood-brain barrier (BBB) cause the prevention and …

A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation

J Williams, FN Iheagwam… - … of Physiology-Cell …, 2024 - journals.physiology.org
Pulmonary hypertension (PH) is a progressive vascular disease characterized by vascular
remodeling, stiffening, and luminal obstruction, driven by dysregulated cell proliferation …

The Promising Role of Selenium and Yeast in the Fight Against Protein Amyloidosis

M Kieliszek, K Sapazhenkava - Biological Trace Element Research, 2024 - Springer
In recent years, increasing attention has been paid to research on diseases related to the
deposition of misfolded proteins (amyloids) in various organs. Moreover, modern scientists …

Ameliorative anti-coagulant, anti-oxidative and anti-ferroptotic activities of nanocurcumin and donepezil on coagulation, oxidation and ferroptosis in Alzheimer's …

NF Nawar, DM Beltagy, TM Mohamed… - Toxicology …, 2024 - academic.oup.com
Alzheimer's disease (ad) is a neurological condition that worsens over time and is
characterized by the buildup of amyloid (Aβ) plaques in the brain parenchyma …

ATTR-and AFib amyloid-two different types of amyloid in the annular ligament of trigger finger

C Treitz, N Müller-Marienburg, RR Meliß, P Urban… - Amyloid, 2023 - Taylor & Francis
Introduction Histological examination of tissue specimens obtained during surgical treatment
of trigger finger frequently encountered unclassifiable amyloid deposits in the annular …

Novel 6, 7-dimethoxyquinazolin-4 (3H)-one derivatives as promising compounds for the therapy of alzheimer's disease

DI Pozdnyakov, AS Chiryapkin… - Problems of Biological …, 2023 - journals.eco-vector.com
Relevance. Alzheimer's disease is one of the most common forms of dementia with a high
mortality and disability rate. Some quinazolinone derivatives having methoxy groups in the …

Investigating Coagulation Mediators Fibrinogen and Platelets in Abdominal Aortic Aneurysm Pathophysiology

HM Russell - 2021 - search.proquest.com
Proteins and mediators of the coagulation cascade have been long found in association with
abdominal aortic aneurysm (AAA). Specifically, the coagulant protein fibrinogen, and …