Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …

Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …

Importance Mild traumatic brain injury (mTBI), or concussion, in children is a rapidly growing
public health concern because epidemiologic data indicate a marked increase in the …

Background More than 50 million people worldwide sustain a traumatic brain injury (TBI)
annually. Detection of intracranial injuries relies on head CT, which is overused and …

Importance Annually in the United States, at least 3.5 million people seek medical attention
for traumatic brain injury (TBI). The development of therapies for TBI is limited by the …

Biomarkers can be broadly defined as qualitative or quantitative measurements that convey
information on the physiopathological state of a subject at a certain time point or disease …

Objectives To determine whether a panel of blood-based biomarkers can discriminate
between patients with suspected mild traumatic brain injury (mTBI) with and without …

Objective To investigate the role of salivary small non-coding RNAs (sncRNAs) in the
diagnosis of sport-related concussion. Methods Saliva was obtained from male professional …

Biomarkers such as calcium channel binding protein S100 subunit beta (S100B), glial
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …

Accurate diagnosis of traumatic brain injury (TBI) is critical to effective management and
intervention, but can be challenging in patients with mild TBI. A substantial number of …