The genetic epidemiology of substance use disorder: A review

EC Prom-Wormley, J Ebejer, DM Dick… - Drug and alcohol …, 2017 - Elsevier
Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

Identification and management of alcohol withdrawal syndrome

A Mirijello, C D'Angelo, A Ferrulli, G Vassallo… - Drugs, 2015 - Springer
Symptoms of alcohol withdrawal syndrome (AWS) may develop within 6–24 h after the
abrupt discontinuation or decrease of alcohol consumption. Symptoms can vary from …

[HTML][HTML] EASL clinical practical guidelines: management of alcoholic liver disease

European Association For The Study Of The Liver - Journal of hepatology, 2012 - Elsevier
Alcoholic liver disease (ALD) is the most prevalent cause of advanced liver disease in
Europe. However, there has been limited research investment into ALD despite its …

Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled …

G Addolorato, L Leggio, A Ferrulli, S Cardone… - The Lancet, 2007 - thelancet.com
Background Intervention to achieve alcohol abstinence represents the most effective
treatment for alcohol-dependent patients with liver cirrhosis; however, anticraving drugs …

[HTML][HTML] Alcohol withdrawal syndrome: benzodiazepines and beyond

A Sachdeva, M Choudhary… - Journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Alcohol dependence is an increasing and pervasive problem. Alcohol withdrawal symptoms
are a part of alcohol dependence syndrome and are commonly encountered in general …

Treatment of alcohol use disorders in patients with alcoholic liver disease

G Addolorato, A Mirijello, P Barrio, A Gual - Journal of hepatology, 2016 - Elsevier
Alcohol use disorders (AUDs) is one of the leading causes of disease and disability in
almost all European countries. Among the alcohol-related diseases, alcoholic liver disease …

Acute alcohol intoxication

L Vonghia, L Leggio, A Ferrulli, M Bertini… - European journal of …, 2008 - Elsevier
Acute alcohol intoxication is a clinically harmful condition that usually follows the ingestion of
a large amount of alcohol. Clinical manifestations are heterogeneous and involve different …

Benzodiazepines for alcohol withdrawal

L Amato, S Minozzi, S Vecchi… - Cochrane Database of …, 2010 - cochranelibrary.com
Background Alcohol abuse and dependence represents a serious health problem
worldwide with social, interpersonal and legal interpolations. Benzodiazepines have been …

Efficacy and safety of baclofen for alcohol dependence: a randomized, double‐blind, placebo‐controlled trial

JC Garbutt, AB Kampov‐Polevoy… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Background: Recent clinical trials and case‐reports indicate that baclofen, a GABAB agonist,
may have efficacy for alcohol dependence. Baclofen has been shown to enhance …

The alcohol withdrawal syndrome

A McKeon, MA Frye, N Delanty - Journal of Neurology, Neurosurgery …, 2008 - jnnp.bmj.com
The alcohol withdrawal syndrome (AWS) is a common management problem in hospital
practice for neurologists, psychiatrists and general physicians alike. Although some patients …