G Liu, C Yang, X Wang, X Chen, Y Wang, W Le - Redox Biology, 2023 - Elsevier
Oxygen metabolism abnormality plays a crucial role in the pathogenesis of Alzheimer's disease (AD) via several mechanisms, including hypoxia, oxidative stress, and …
T Peng, S Li, L Liu, C Yang, M Farhan… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Ischemic stroke is characterized by the presence of both brain ischemic and reperfusion- induced injuries in the brain, leading to neuronal dysfunction and death. Artemisinin, an FDA …
M Ding, R Shi, F Fu, M Li, D De, Y Du, Z Li - Journal of Advanced Research, 2023 - Elsevier
Introduction The anti-cancer medication doxorubicin (Dox) is largely restricted in clinical usage due to its significant cardiotoxicity. The only medication approved by the FDA for Dox …
X Zhao, X Huang, C Yang, Y Jiang, W Zhou… - International journal of …, 2022 - mdpi.com
The abnormal immune response is an early change in the pathogenesis of Alzheimer's disease (AD). Microglial activation is a crucial regulator of the immune response, which …
M Chen, Y Chen, W Zhu, X Yan, J Xiao, P Zhang… - Biomedicine & …, 2023 - Elsevier
Diabetic nephropathy (DN) is one of the serious complications of diabetes mellitus, primarily arising from type 2 diabetes (T2DM), and can progress to chronic kidney disease (CKD) and …
Q Li, L Rubin, M Silva, S Li, C Yang… - Oxidative Medicine …, 2022 - Wiley Online Library
Aging is associated with the occurrence of diverse degenerative changes in various tissues and organs and with an increased incidence of neurological disorders, especially …
QQ Pang, JH Kim, HY Kim, JH Kim, EJ Cho - Molecules, 2023 - mdpi.com
This study aims to investigate the protective effects and mechanisms of pectolinarin against oxidative stress-induced cell damage in SH-SY5Y cells. Neurodegenerative diseases—such …
Q Li, S Li, J Fang, C Yang, X Zhao, Q Wang, W Zhou… - Molecules, 2023 - mdpi.com
Parkinson's disease (PD) is an age-related, progressive neurodegenerative disease characterized by the gradual and massive loss of dopaminergic neurons in the substantia …
W Tian, S Heo, DW Kim, IS Kim, D Ahn, HJ Tae… - International Journal of …, 2021 - mdpi.com
Free radical generation and oxidative stress push forward an immense influence on the pathogenesis of neurodegenerative diseases such as Alzheimer's disease and Parkinson's …