Mesenchymal stem cells: cell fate decision to osteoblast or adipocyte and application in osteoporosis treatment

L Hu, C Yin, F Zhao, A Ali, J Ma, A Qian - International Journal of …, 2018 - mdpi.com
Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and
degraded bone microstructure, which leads to increased bone fragility and risks of bone …

Review of signaling pathways governing MSC osteogenic and adipogenic differentiation

AW James - Scientifica, 2013 - Wiley Online Library
Mesenchymal stem cells (MSC) are multipotent cells, functioning as precursors to a variety
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …

Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease

AR Williams, JM Hare - Circulation research, 2011 - Am Heart Assoc
Mesenchymal stem cells (MSCs) are a prototypical adult stem cell with capacity for self-
renewal and differentiation with a broad tissue distribution. Initially described in bone …

Running against the Wnt: How Wnt/β-catenin suppresses adipogenesis

TJJ De Winter, R Nusse - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) give rise to adipocytes, osteocytes, and chondrocytes and
reside in various tissues, including bone marrow and adipose tissue. The differentiation …

[HTML][HTML] Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood

W Wagner, F Wein, A Seckinger, M Frankhauser… - Experimental …, 2005 - Elsevier
OBJECTIVE: Various preparative protocols have been proposed for the acquisition and
cultivation of mesenchymal stem cells (MSC). Whereas surface antigen markers have failed …

Mesenchymal stromal cells: biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation

CM Kolf, E Cho, RS Tuan - Arthritis research & therapy, 2007 - Springer
Recent advances in understanding the cellular and molecular signaling pathways and
global transcriptional regulators of adult mesenchymal stem cells have provided new …

Mesenchymal stem cells for the treatment of neurodegenerative disease

N Joyce, G Annett, L Wirthlin, S Olson… - Regenerative …, 2010 - Taylor & Francis
Mesenchymal stem cells/marrow stromal cells (MSCs) present a promising tool for cell
therapy, and are currently being tested in US FDA-approved clinical trials for myocardial …

Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential

JE Frith, B Thomson, PG Genever - Tissue Engineering Part C …, 2010 - liebertpub.com
Mesenchymal stem cells (MSCs) are capable of self-renewal and differentiation along the
osteogenic, chondrogenic, and adipogenic lineages and have potential applications in a …

Update on Wnt signaling in bone cell biology and bone disease

DG Monroe, ME McGee-Lawrence, MJ Oursler… - Gene, 2012 - Elsevier
For more than a decade, Wnt signaling pathways have been the focus of intense research
activity in bone biology laboratories because of their importance in skeletal development …