Biology and pathogenesis of the evolutionarily successful, obligate human bacterium Neisseria meningitidis

DS Stephens - Vaccine, 2009 - Elsevier
For at least two hundred years, Neisseria meningitidis (the meningococcus), the cause of
epidemic meningitis and sepsis, has inflicted rapid death, disability and fear on disparate …

Lipid A phosphoethanolamine transferase: regulation, structure and immune response

A Samantha, A Vrielink - Journal of molecular biology, 2020 - Elsevier
A wide variety of antibiotics are targeted to the bacterial membrane due to its unique
arrangement and composition relative to the host mammalian membranes. By modification …

Genome Sequence of the Endosymbiont Rickettsia peacockii and Comparison with Virulent Rickettsia rickettsii: Identification of Virulence Factors

RF Felsheim, TJ Kurtti, UG Munderloh - PloS one, 2009 - journals.plos.org
Rickettsia peacockii, also known as the East Side Agent, is a non-pathogenic obligate
intracellular bacterium found as an endosymbiont in Dermacentor andersoni ticks in the …

The multifaceted roles of phosphoethanolamine-modified lipopolysaccharides: from stress response and virulence to cationic antimicrobial resistance

A Schumann, A Gaballa… - … and Molecular Biology …, 2024 - journals.asm.org
Lipopolysaccharides (LPS) are an integral part of the outer membrane of Gram-negative
bacteria and play essential structural and functional roles in maintaining membrane integrity …

Biosynthetically engineered lipopolysaccharide as vaccine adjuvant

A Zariri, P van der Ley - Expert review of vaccines, 2015 - Taylor & Francis
Lipopolysaccharide (LPS), a dominant component of the Gram-negative bacterial outer
membrane, is a strong activator of the innate immune system, and thereby an important …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2007–2008

DJ Harvey - Mass spectrometry reviews, 2012 - Wiley Online Library
This review is the fifth update of the original review, published in 1999, on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

Neisseria meningitidis Translation Elongation Factor P and Its Active-Site Arginine Residue Are Essential for Cell Viability

T Yanagisawa, H Takahashi, T Suzuki, A Masuda… - PLoS …, 2016 - journals.plos.org
Translation elongation factor P (EF-P), a ubiquitous protein over the entire range of bacterial
species, rescues ribosomal stalling at consecutive prolines in proteins. In Escherichia coli …

Phosphoethanolamine residues on the lipid A moiety of Neisseria gonorrhoeae lipooligosaccharide modulate binding of complement inhibitors and resistance to …

LA Lewis, WM Shafer, T Dutta Ray, S Ram… - Infection and …, 2013 - Am Soc Microbiol
Loss of phosphoethanolamine (PEA) from the lipid A of gonococcal strain FA19 results in
increased sensitivity to killing by the classical pathway of complement. Here we demonstrate …

Proteomic approach to identify host cell attachment proteins provides protective Pseudomonas aeruginosa vaccine antigen FtsZ

I Jurado-Martín, J Tomás-Cortázar, Y Hou… - npj Vaccines, 2024 - nature.com
Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that causes severe
nosocomial infections in susceptible individuals due to the emergence of multidrug-resistant …

In-silico prediction and deep-DNA sequencing validation indicate phase variation in 115 Neisseria meningitidis genes

E Siena, R D'Aurizio, D Riley, H Tettelin, S Guidotti… - BMC genomics, 2016 - Springer
Abstract Background The Neisseria meningitidis (Nm) chromosome shows a high
abundance of simple sequence DNA repeats (SSRs) that undergo stochastic, reversible …