The cell biology of caveolae is a rapidly growing area of biomedical research. Caveolae are
known primarily for their ability to transport molecules across endothelial cells, but modern …

▪ Abstract Endocytosis in eukaryotic cells is characterized by the continuous and regulated
formation of prolific numbers of membrane vesicles at the plasma membrane. These …

Among the membrane compartments of a cell, vesicles known as “caveolae” have long
defied functional characterization. However, since the identification of a family of proteins …

An essential property of the plasma membrane of mammalian cells is its plasticity, which is
required for sensing and transmitting of signals, and for accommodating the tensional …

▪ Abstract Endothelial nitric oxide synthase (eNOS) is expressed in vascular endothelium,
airway epithelium, and certain other cell types where it generates the key signaling molecule …

Renal function is highly dependent on endothelium-derived nitric oxide (NO). Several renal
disorders have been linked to impaired NO bioavailability. The enzyme that is responsible …

The membrane association of endothelial nitric oxide synthase (eNOS) plays an important
role in the biosynthesis of nitric oxide (NO) in vascular endothelium. Previously, we have …

The complex regulation of eNOS (endothelial nitric oxide synthase) in cardiovascular
physiology occurs at multiple stages. eNOS mRNA levels are controlled both at the …

Caveolin is a 22-kDa membrane protein found associated with a coat material decorating
the inner membrane surface of caveolae. A remarkable feature of this protein is its ability to …

Caveolae are specialized plasmalemmal microdomains originally studied in numerous cell
types for their involvement in the transcytosis of macromolecules. They are enriched in …