Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …

Noninvasive human neuroimaging has yielded many discoveries about the brain. Numerous
methodological advances have also occurred, though inertia has slowed their adoption. This …

While the role of cortical microstructure in organising neural function is well established, it
remains unclear how structural constraints can give rise to more flexible elements of …

Hierarchy provides a unifying principle for the macroscale organization of anatomical and
functional properties across primate cortex, yet microscale bases of specialization across …

Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

The study of brain plasticity has tended to focus on the synapse, where well-described
activity-dependent mechanisms are known to play a key role in learning and memory …

Abstract The Developing Human Connectome Project (dHCP) seeks to create the first 4-
dimensional connectome of early life. Understanding this connectome in detail may provide …

Human cortex appears to thin during childhood development. However, the underlying
microstructural mechanisms are unknown. Using functional magnetic resonance imaging …

Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

The superior longitudinal fasciculus (SLF) is part of the longitudinal association fiber system,
which lays connections between the frontal lobe and other areas of the ipsilateral …