Global distribution of rotavirus serotypes/genotypes and its implication for the development and implementation of an effective rotavirus vaccine

N Santos, Y Hoshino - Reviews in medical virology, 2005 - Wiley Online Library
A safe and effective rotavirus vaccine is urgently needed, particularly in developing
countries. Critical to vaccine development and implementation is a knowledge base …

Rotavirus serotypes: classification and importance in epidemiology, immunity, and vaccine development

Y Hoshino, AZ Kapikian - Journal of Health, Population and Nutrition, 2000 - JSTOR
The development and implementation of safe and effective vaccines to prevent the
enormous health burden of rotavirus-associated disease is a global public health goal …

Evidence of high-frequency genomic reassortment of group A rotavirus strains in Bangladesh: emergence of type G9 in 1995

LE Unicomb, G Podder, JR Gentsch… - Journal of Clinical …, 1999 - Am Soc Microbiol
ABSTRACT We characterized 1,534 rotavirus (RV) strains collected in Bangladesh from
1992 to 1997 to assess temporal changes in G type and to study the most common G and P …

Rotavirus strain diversity in Blantyre, Malawi, from 1997 to 1999

NA Cunliffe, JS Gondwe, SM Graham… - Journal of clinical …, 2001 - Am Soc Microbiol
In a 2-year study of viral gastroenteritis in children in Blantyre, Malawi, the diversity of
rotavirus strains was investigated by using electropherotyping, reverse transcription-PCR …

Burden and typing of rotavirus group A in Latin America and the Caribbean: systematic review and meta‐analysis

AC Linhares, JA Stupka, A Ciapponi… - Reviews in Medical …, 2011 - Wiley Online Library
The efficacy of licensed rotavirus vaccines has only been shown against certain rotavirus
group A (RV‐A) types. It is critical to understand the burden of rotavirus gastroenteritis …

Prevalence and genetic diversity of human astroviruses in Mexican children with symptomatic and asymptomatic infections

M Méndez-Toss, DD Griffin, J Calva… - Journal of clinical …, 2004 - Am Soc Microbiol
The prevalence and type diversity of human astroviruses (HAstV) in children with
symptomatic and asymptomatic infections were determined in five localities of Mexico …

Monovalent rotavirus vaccine provides protection against an emerging fully heterotypic G9P [4] rotavirus strain in Mexico

C Yen, JR Figueroa, ES Uribe… - Journal of Infectious …, 2011 - academic.oup.com
After the introduction of monovalent rotavirus vaccine (RV1) in Mexico in 2006–2007,
diarrhea mortality and morbidity declined substantially among Mexican children under 5 …

Genotype profiles of rotavirus strains from children in a suburban community in Guinea-Bissau, Western Africa

TK Fischer, H Steinsland, K Mølbak, R Ca… - Journal of clinical …, 2000 - Am Soc Microbiol
ABSTRACT The P (VP4) and G (VP7) genotypes of 167 group A rotavirus strains obtained
during the period 1996 to 1998 from 149 children living in a suburban community in Guinea …

Reductions in cross‐neutralizing antibody responses in infants after attenuation of the human rotavirus vaccine candidate 89‐12

RL Ward, CD Kirkwood, DS Sander… - The Journal of …, 2006 - academic.oup.com
Abstract The G1P1A [8] rotavirus vaccine candidate 89‐12, the precursor to Rotarix,
stimulated high titers of neutralizing antibodies to non‐G1/P1A [8] serotypes of human …

The internal rotavirus protein VP6 primes for an enhanced neutralizing antibody response

FR Esquivel, S Lopez, L Guitierrez-x, C Arias - Archives of virology, 2000 - Springer
We studied in the rotavirus system whether the internal protein VP6 could prime for an
enhancement in the production of neutralizing antibodies (NeuAb) against the external …