Three terms are commonly used interchangeably to identify vulnerable older adults:
comorbidity, or multiple chronic conditions, frailty, and disability. However, in geriatric …

The concept of frailty as a medically distinct syndrome has evolved based on the clinical
experience of geriatricians and is clinically well recognizable. Frailty is a nonspecific state of …

Objective To validate the FRAIL scale. Design Longitudinal study. Setting Community.
Participants Representative sample of African Americans age 49 to 65 years at onset of …

Background. There is no consensus regarding the definition of frailty for clinical uses.
Methods. A modified Delphi process was used to attempt to achieve consensus definition …

Background The biological basis of frailty has been difficult to establish owing to the lack of a
standard definition, its complexity, and its frequent coexistence with illness. Objective To …

Over the past century, the world has seen unprecedented declines in mortality rates, leading
to an accelerated increase in the world population. This century will realise falling fertility …

Background. Frailty and fitness are important attributes of older persons, but population
samples of their prevalence, attributes, and outcomes are limited. Methods. The authors …

INTRODUCTION: There are many different conceptual definitions of frailty in circulation.
Most of these definitions focus mainly on physical problems affecting older people. Only a …

BACKGROUND: Frailty is a state of increased vulnerability to health-related stressors and
can be measured by summing the number of frailty characteristics present in an individual …

OBJECTIVES: To determine specific physiological correlates of the geriatric syndrome of
frailty that warrant further investigation. DESIGN: Population‐based case‐control study …