The role of natural products in drug discovery and development against neglected tropical diseases

PM Cheuka, G Mayoka, P Mutai, K Chibale - Molecules, 2016 - mdpi.com
Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …

Marine pharmacology in 2009–2011: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral …

AMS Mayer, AD Rodríguez, O Taglialatela-Scafati… - Marine drugs, 2013 - mdpi.com
The peer-reviewed marine pharmacology literature from 2009 to 2011 is presented in this
review, following the format used in the 1998–2008 reviews of this series. The …

Antiplasmodial natural products: an update

N Tajuddeen, FR Van Heerden - Malaria journal, 2019 - Springer
Background Malaria remains a significant public health challenge in regions of the world
where it is endemic. An unprecedented decline in malaria incidences was recorded during …

Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural product …, 2012 - pubs.rsc.org
Covering: 2010. Previous review: Nat. Prod. Rep., 2011, 28, 196 This review covers the
literature published in 2010 for marine natural products, with 895 citations (590 for the …

Biomaterials and bioactive natural products from marine invertebrates: From basic research to innovative applications

G Romano, M Almeida, A Varela Coelho, A Cutignano… - Marine Drugs, 2022 - mdpi.com
Aquatic invertebrates are a major source of biomaterials and bioactive natural products that
can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2004 - pubs.rsc.org
Covering: 2002. Previous review: Nat. Prod. Rep., 2003, 20, 1 This review covers the
literature published in 2002 for marine natural products, with 579 citations (413 for the …

Searching for drugs for Chagas disease, leishmaniasis and schistosomiasis: a review

SS Santos, RV de Araújo, J Giarolla, O El Seoud… - International journal of …, 2020 - Elsevier
Chagas disease, leishmaniasis and schistosomiasis are neglected diseases (NDs) and are
a considerable global challenge. Despite the huge number of people infected, NDs do not …

Saponins as cytotoxic agents: an update (2010–2018). Part I—steroidal saponins

D Sobolewska, A Galanty, K Grabowska… - Phytochemistry …, 2020 - Springer
Steroidal saponins are a group of glycosides widely distributed among monocotyledonous
families. They exert a wide spectrum of biological effects including cytotoxic and antitumor …

Current approaches to discover marine antileishmanial natural products

AG Tempone, CM de Oliveira, RGS Berlinck - Planta medica, 2011 - thieme-connect.com
Leishmaniasis is a neglected infectious disease caused by kinetoplastid protozoans. An
urgent need for novel chemotherapeutics exists. The current approaches to discover new …

Screening marine natural products for new drug leads against trypanosomatids and malaria

M Álvarez-Bardón, Y Pérez-Pertejo, C Ordóñez… - Marine Drugs, 2020 - mdpi.com
Neglected Tropical Diseases (NTD) represent a serious threat to humans, especially for
those living in poor or developing countries. Almost one-sixth of the world population is at …