Novel FOXF1-stabilizing compound tanfe stimulates lung angiogenesis in alveolar capillary dysplasia
Rationale: Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) is
linked to heterozygous mutations in the FOXF1 (Forkhead Box F1) gene, a key …
linked to heterozygous mutations in the FOXF1 (Forkhead Box F1) gene, a key …
CRISPR-Cas9 genome editing allows generation of the mouse lung in a rat
Rationale: Recent efforts in bioengineering and embryonic stem cell (ESC) technology
allowed the generation of ESC-derived mouse lung tissues in transgenic mice that were …
allowed the generation of ESC-derived mouse lung tissues in transgenic mice that were …
An artificial LAMA2-GelMA hydrogel microenvironment for the development of pancreatic endocrine progenitors
Y Huang, Y Xu, J Zhu, J Wan, Y Xiong, Z Jiang, S Zhu… - Biomaterials, 2022 - Elsevier
The biomimetic pancreatic microenvironment improves the differentiation efficiency and
function of human embryonic stem cell-derived β-cells (S C-β cells). Thus, a laminin subunit …
function of human embryonic stem cell-derived β-cells (S C-β cells). Thus, a laminin subunit …
Generation of allogeneic and xenogeneic functional muscle stem cells for intramuscular transplantation
A Lenardič, SA Domenig, J Zvick, N Bundschuh… - The Journal of Clinical …, 2024 - jci.org
Satellite cells, the stem cells of skeletal muscle tissue, hold a remarkable regeneration
capacity and therapeutic potential in regenerative medicine. However, low satellite cell yield …
capacity and therapeutic potential in regenerative medicine. However, low satellite cell yield …
The impact of induced pluripotent stem cells in animal conservation
Y Wu, C Wang, X Fan, Y Ma, Z Liu, X Ye… - Veterinary Research …, 2024 - Springer
It is widely acknowledged that we are currently facing a critical tipping point with regards to
global extinction, with human activities driving us perilously close to the brink of a …
global extinction, with human activities driving us perilously close to the brink of a …
The bone marrow of mouse-rat chimeras contains progenitors of multiple pulmonary cell lineages
Radiation-induced lung injury (RILI) is a common complication of anti-cancer treatments for
thoracic and hematologic malignancies. Bone marrow (BM) transplantation restores …
thoracic and hematologic malignancies. Bone marrow (BM) transplantation restores …
Transplantation of Alveolar Macrophages Improves the Efficacy of Endothelial Progenitor Cell Therapy in Mouse Model of Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is a severe complication of preterm births, which
develops due to exposure to supplemental oxygen and mechanical ventilation. Published …
develops due to exposure to supplemental oxygen and mechanical ventilation. Published …
[PDF][PDF] 1State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China 2Key Laboratory of …
C Huang, H Jiang, J Dong, L Jiang, J Li, J Xu, T Cui… - researchgate.net
Liver disease is a major global health challenge. There is a shortage of liver donors
worldwide, and hepatocyte transplantation (HT) may be an effective treatment to overcome …
worldwide, and hepatocyte transplantation (HT) may be an effective treatment to overcome …
Functional mouse hepatocytes derived from interspecies chimeric livers effectively mitigate chronic liver fibrosis
C Huang, H Jiang, J Dong, L Jiang, J Li, J Xu, T Cui… - Stem Cell Reports, 2024 - cell.com
Liver disease is a major global health challenge. There is a shortage of liver donors
worldwide, and hepatocyte transplantation (HT) may be an effective treatment to overcome …
worldwide, and hepatocyte transplantation (HT) may be an effective treatment to overcome …