Advances in engineering near-infrared luminescent materials

CT Jackson, S Jeong, GF Dorlhiac, MP Landry - Iscience, 2021 - cell.com
Near-infrared (NIR) luminescent materials have emerged as a growing field of interest,
particularly for imaging and optics applications in biology, chemistry, and physics. However …

The near-infrared-II fluorophores and advanced microscopy technologies development and application in bioimaging

P Liu, X Mu, XD Zhang, D Ming - Bioconjugate Chemistry, 2019 - ACS Publications
The interaction between light and tissue such as absorption and scattering limits the
penetration depth and spatiotemporal resolution of in vivo fluorescence bioimaging in a …

[HTML][HTML] VTA glutamatergic neurons mediate innate defensive behaviors

MF Barbano, HL Wang, S Zhang, J Miranda-Barrientos… - Neuron, 2020 - cell.com
The ventral tegmental area (VTA) has dopamine, GABA, and glutamate neurons, which have
been implicated in reward and aversion. Here, we determined whether VTA-glutamate or …

Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model

LA Kasatkina, C Ma, ME Matlashov, T Vu, M Li… - Nature …, 2022 - nature.com
Optogenetic manipulation and optical imaging in the near-infrared range allow non-invasive
light-control and readout of cellular and organismal processes in deep tissues in vivo. Here …

Near-infrared fluorescent proteins: multiplexing and optogenetics across scales

DM Shcherbakova, OV Stepanenko, KK Turoverov… - Trends in …, 2018 - cell.com
Since mammalian tissue is relatively transparent to near-infrared (NIR) light, NIR fluorescent
proteins (FPs) engineered from bacterial phytochromes have become widely used probes …

Fast widefield imaging of neuronal structure and function with optical sectioning in vivo

Z Li, Q Zhang, SW Chou, Z Newman, R Turcotte… - Science …, 2020 - science.org
Optical microscopy, owing to its noninvasiveness and subcellular resolution, enables in vivo
visualization of neuronal structure and function in the physiological context. Optical …

GDNF/RET signaling pathway activation eliminates Lewy body pathology in midbrain dopamine neurons

P Chmielarz, Ş Er, J Konovalova, L Bandres… - Movement …, 2020 - Wiley Online Library
Background Parkinson's disease (PD) is associated with proteostasis disturbances and
accumulation of misfolded α‐synuclein (α‐syn), a cytosolic protein present in high …

Near-infrared fluorescent proteins and their applications

MM Karasev, OV Stepanenko, KA Rumyantsev… - Biochemistry …, 2019 - Springer
High transparency, low light-scattering, and low autofluorescence of mammalian tissues in
the near-infrared (NIR) spectral range (~ 650–900 nm) open a possibility for in vivo imaging …

Thermodynamic implications and time evolution of the interactions of near-infrared PbS quantum dots with human serum albumin

Q Wang, WQ Chen, XY Liu, Y Liu, FL Jiang - ACS omega, 2021 - ACS Publications
Near-infrared (NIR)-emitting PbS quantum dots (QDs) are endowed with good stability, high
quantum yield, and long lifetime in the body, so they are promising agents in biological …

Fluorescent nanotechnology for in vivo imaging

Z Guo, Z Cui - Wiley Interdisciplinary Reviews: Nanomedicine …, 2021 - Wiley Online Library
Fluorescent imaging in living animals gives an intuitive picture of the dynamic processes in
the complex environment within a living being. However, animal tissues present a …