Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …

Detection of circulating tumor DNAs (ctDNAs) in cancer patients is an important component
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …

Background Liquid biopsy has been widely researched for early diagnosis, prognostication
and disease monitoring in lung cancer, but there is a need to investigate its clinical utility for …

Blood circulating cell-free DNA (ccfDNA) is a suggested biosource of valuable clinical
information for cancer, meeting the need for a minimally-invasive advancement in the route …

Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐
time follow‐up of cancer and overcomes many limitations of tissue biopsies. Epigenetic …

Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …

Epigenetic modifications and regulators represent potential molecular elements which
control relevant physiological and pathological features, thereby contributing to the natural …

Currently, early detection of lung cancer relies on the characterisation of images generated
from computed tomography (CT). However, lung tissue biopsy, a highly invasive surgical …

Checkpoint inhibitor therapy constitutes a promising cancer treatment strategy that targets
the immune checkpoints to re-activate silenced T cell cytotoxicity. In recent pivotal trials …