Biomaterials for tissue engineering applications

TJ Keane, SF Badylak - Seminars in pediatric surgery, 2014 - Elsevier
With advancements in biological and engineering sciences, the definition of an ideal
biomaterial has evolved over the past 50 years from a substance that is inert to one that has …

Preventing rejection of the kidney transplant

D Malhotra, P Jethwani - Journal of Clinical Medicine, 2023 - mdpi.com
With increasing knowledge of immunologic factors and with the advent of potent
immunosuppressive agents, the last several decades have seen significantly improved …

[HTML][HTML] Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients

R Ferguson, J Grinyo, F Vincenti, DB Kaufman… - American Journal of …, 2011 - Elsevier
Current immunosuppressive regimens in renal transplantation typically include calcineurin
inhibitors (CNIs) and corticosteroids, both of which have toxicities that can impair recipient …

[HTML][HTML] The impact of acute rejection in kidney transplantation on long-term allograft and patient outcome

M Jalalzadeh, N Mousavinasab, S Peyrovi… - Nephro-urology …, 2015 - ncbi.nlm.nih.gov
Background: Patients with end stage renal disease (ESRD) can be sustained with dialysis
therapy. Objectives: In this study, we followed up the effect of early acute and late acute …

Transplantation with kidneys retrieved from deceased donors with acute renal failure

R Klein, NZ Galante, TV de Sandes-Freitas… - …, 2013 - journals.lww.com
Background The discard rate of kidneys recovered from deceased donors with acute renal
failure (ARF) is higher compared with those without ARF mainly due to the uncertainty …

Genetic and clinical determinants of early, acute calcineurin inhibitor-related nephrotoxicity: results from a kidney transplant consortium

PA Jacobson, D Schladt, A Israni, WS Oetting… - …, 2012 - journals.lww.com
Background. Calcineurin inhibitor (CNI)-related acute nephrotoxicity is a common
complication of transplantation. Clinical factors and elevated CNI levels are associated with …

Analysis of biomarkers within the initial 2 years posttransplant and 5-year kidney transplant outcomes: results from clinical trials in organ transplantation-17

G Faddoul, GN Nadkarni, ND Bridges, J Goebel… - …, 2018 - journals.lww.com
Background An early posttransplant biomarker/surrogate marker for kidney allograft loss has
the potential to guide targeted interventions. Previously published findings, including results …

Early posttransplantation hyperglycemia in kidney transplant recipients is associated with overall long-term graft losses

TG Valderhaug, J Hjelmesæth, T Jenssen… - …, 2012 - journals.lww.com
Background The association of early-onset posttransplantation hyperglycemia with long-
term renal allograft survival is unknown. Methods Seventy-one (SD 9) days after …

Higher tacrolimus trough levels and time in the therapeutic range are associated with the risk of acute rejection in the first month after renal transplantation

TVA Nguyen, HD Nguyen, TLH Nguyen, VT Le… - BMC nephrology, 2023 - Springer
Background Tacrolimus trough levels (C0) are used in most transplant centres for
therapeutic drug monitoring (TDM) of tacrolimus (Tac). The target range of Tac C0 has been …

[HTML][HTML] The Korean Organ Transplantation Registry (KOTRY): an overview and summary of the kidney-transplant cohort

HJ Jeon, TY Koo, MK Ju, DW Chae… - Kidney Research and …, 2022 - ncbi.nlm.nih.gov
Background As the need for a nationwide organ-transplant registry emerged, a prospective
registry, the Korean Organ Transplantation Registry (KOTRY), was initiated in 2014. Here …