The neuropeptide oxytocin has been in the focus of scientists for decades due to its
profound and pleiotropic effects on physiology, activity of neuronal circuits and behaviors …

TRPV1 has been originally cloned as the heat and capsaicin receptor implicated in acute
pain signalling, while further research has shifted the focus to its importance in chronic pain …

Several gastrointestinal (GI) tract abnormalities, including visceral hypersensitivity, motility,
and intestinal permeability alterations, have been implicated in functional GI disorders …

The rostral agranular insular cortex (RAIC) is a relevant structure in nociception. Indeed,
recruitment of GABAergic activity in RAIC promotes the disinhibition of the locus ceruleus …

The research program on oxytocin started in 1895, when Oliver and Schafer reported that a
substance extracted from the pituitary gland elevates blood pressure when injected …

Oxytocin possesses several physiological and social functions, among which an important
analgesic effect. For this purpose, oxytocin binds mainly to its unique receptor, both in the …

Simple Summary Although the pain associated with parturition performs the primary
physiological function of maintaining frequent, strong myometrial contractions, its biological …

Based on the abundance of scientific publications, the polymodal sensor TRPV1 is known
as one of the most studied proteins within the TRP channel family. This receptor has been …

Oxytocinergic transmission blocks nociception at the peripheral, spinal, and supraspinal
levels through the oxytocin receptor (OTR). Indeed, a neuronal pathway from the …

We explored the involvement of oxytocin receptor (Oxtr)/transient-receptor-potential-vanilloid-
1 (TRPV1) genes and oxytocin (Oxt) on the adaptation of skeletal muscle to cold stress …