Tubulin polyglutamylation differentially regulates microtubule‐interacting proteins

M Genova, L Grycova, V Puttrich, MM Magiera… - The EMBO …, 2023 - embopress.org
Tubulin posttranslational modifications have been predicted to control cytoskeletal functions
by coordinating the molecular interactions between microtubules and their associating …

Bioimage analysis and cell motility

A Boquet-Pujadas, JC Olivo-Marin, N Guillén - Patterns, 2021 - cell.com
Bioimage analysis (BIA) has historically helped study how and why cells move; biological
experiments evolved in intimate feedback with the most classical image processing …

A mechanism for sustained cellulose synthesis during salt stress

A Endler, C Kesten, R Schneider, Y Zhang, A Ivakov… - Cell, 2015 - cell.com
Abiotic stress, such as salinity, drought, and cold, causes detrimental yield losses for all
major plant crop species. Understanding mechanisms that improve plants' ability to produce …

Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes

V Siahaan, J Krattenmacher, AA Hyman, S Diez… - Nature cell …, 2019 - nature.com
Tau is an intrinsically disordered protein, which diffuses on microtubules. In
neurodegenerative diseases, collectively termed tauopathies, malfunction of tau and its …

An overview of methods for cardiac rhythm detection in zebrafish

F Santoso, A Farhan, AL Castillo, N Malhotra… - Biomedicines, 2020 - mdpi.com
The heart is the most important muscular organ of the cardiovascular system, which pumps
blood and circulates, supplying oxygen and nutrients to peripheral tissues. Zebrafish have …

Tracking single particles and elongated filaments with nanometer precision

F Ruhnow, D Zwicker, S Diez - Biophysical journal, 2011 - cell.com
Recent developments in image processing have greatly advanced our understanding of
biomolecular processes in vitro and in vivo. In particular, using Gaussian models to fit the …

Parallel computation with molecular-motor-propelled agents in nanofabricated networks

DV Nicolau Jr, M Lard, T Korten… - Proceedings of the …, 2016 - National Acad Sciences
The combinatorial nature of many important mathematical problems, including
nondeterministic-polynomial-time (NP)-complete problems, places a severe limitation on the …

The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants

C Kesten, A Wallmann, R Schneider… - Nature …, 2019 - nature.com
Microtubules are filamentous structures necessary for cell division, motility and morphology,
with dynamics critically regulated by microtubule-associated proteins (MAPs). Here we …

FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeleton

C Aquino-Perez, M Safaralizade, R Podhajecky… - Proceedings of the …, 2024 - pnas.org
Precise segregation of chromosomes during mitosis requires assembly of a bipolar mitotic
spindle followed by correct attachment of microtubules to the kinetochores. This highly …

Tubulin Acetylation Alone Does Not Affect Kinesin-1 Velocity and Run Length In Vitro

WJ Walter, V Beranek, E Fischermeier, S Diez - 2012 - journals.plos.org
Kinesin-1 plays a major role in anterograde transport of intracellular cargo along
microtubules. Currently, there is an ongoing debate of whether α-tubulin K40 acetylation …