The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

Detailed neuroscientific data from macaque monkeys have been essential in advancing
understanding of human frontal cortex function, particularly for regions of frontal cortex …

Macroscopic neuroimaging modalities in humans have revealed the organization of brain-
wide activity into distributed functional networks that re-organize according to behavioral …

Visual object memory is a fundamental element of various cognitive abilities, and the
underlying neural mechanisms have been extensively examined especially in the anterior …

The lateral prefrontal cortex (LPFC) of primates plays an important role in executive control,
but how it interacts with the rest of the cortex remains unclear. To address this, we densely …

Goal-directed behavior requires identifying objects in the environment that can satisfy
internal needs and executing actions to obtain those objects. The current study examines …

Choice-relevant brain regions in prefrontal cortex may progressively transform information
about options into choices. Here, we examine responses of neurons in four regions of the …

Reinforcement learning (RL), particularly in primates, is often driven by symbolic outcomes.
However, it is usually studied with primary reinforcers. To examine the neural mechanisms …

Ventrolateral prefrontal cortex (vlPFC), dorsolateral prefrontal cortex (dlPFC), and temporal
cortex (TE) all contribute to visual decision-making. Accumulating evidence suggests that …

Training in working memory tasks is associated with lasting changes in prefrontal cortical
activity. To assess the neural activity changes induced by training, we recorded single units …