Skeletal muscle health is a strong predictor of overall health and longevity. Pathologies affecting skeletal muscle such as cancer cachexia, intensive care unit treatment, muscular …
SF Schmidt, M Rohm, S Herzig, MB Diaz - Trends in cancer, 2018 - cell.com
Cancer cachexia is a multifactorial condition characterized by body weight loss that negatively affects quality of life and survival of patients with cancer. Despite the clinical …
Weight loss is diagnostic of cachexia, a debilitating syndrome contributing mightily to morbidity and mortality in cancer. Most research has probed mechanisms leading to muscle …
AA Narsale, JA Carson - … opinion in supportive and palliative care, 2014 - journals.lww.com
IL-6 remains a promising therapeutic strategy for attenuating cachexia progression with many types of cancer. However, improvement of this treatment will require a better …
C Torregrosa, F Chorin, EEM Beltran, C Neuzillet… - Cancers, 2022 - mdpi.com
Simple Summary This literature review on adapted physical exercise has been written in order to raise awareness of medical staff to this central theme in the management of cancer …
While skeletal muscle mass is an established primary outcome related to understanding cancer cachexia mechanisms, considerable gaps exist in our understanding of muscle …
ML Rossetti, JL Steiner, BS Gordon - Molecular and cellular endocrinology, 2017 - Elsevier
Androgens significantly alter muscle mass in part by shifting protein balance in favor of net protein accretion. During various atrophic conditions, the clinical impact of decreased …
JP Hardee, BR Counts… - American journal of …, 2019 - journals.sagepub.com
Cachexia, the unintentional loss of body weight, is prevalent in many cancer types, and the associated skeletal muscle mass depletion increases patient morbidity and mortality. While …
Cachexia affects about 80% of gastrointestinal cancer patients. This multifactorial syndrome resulting in involuntary and continuous weight loss is accompanied by systemic …