Identification and characterization of pharmaceuticals using Raman and surface‐enhanced Raman scattering

S Cîntǎ Pînzaru, I Pavel, N Leopold… - Journal of Raman …, 2004 - Wiley Online Library
Many recent papers reflect ongoing research and development concerning pharmaceutical
applications of Raman techniques. This short review highlights different Raman techniques …

Hot spots in Ag core− Au shell nanoparticles potent for surface-enhanced Raman scattering studies of biomolecules

GVP Kumar, S Shruthi, B Vibha… - The Journal of …, 2007 - ACS Publications
The vicinity of metallic nanostructures that provides intense optical fields is termed as “hot
spot”. Any molecule in close proximity to these hot spots will give rise to an increased …

Hydrogel implants for transscleral drug delivery for retinoblastoma treatment

AI Cocarta, R Hobzova, J Sirc, T Cerna… - Materials Science and …, 2019 - Elsevier
Retinoblastoma (Rb) is the most common primary malignant intraocular tumor in children
which develops from the retinal stem cells. Systemic chemotherapy is the typical therapeutic …

Methods for elucidation of DNA-anticancer drug interactions and their applications in the development of new drugs

M Misiak, F Mantegazza… - Current pharmaceutical …, 2016 - ingentaconnect.com
DNA damaging agents including anthracyclines, camptothecins and platinum drugs are
among most frequently used drugs in the chemotherapeutic routine. Due to their relatively …

Copper–topotecan complexation mediates drug accumulation into liposomes

AS Taggar, J Alnajim, M Anantha, A Thomas… - Journal of controlled …, 2006 - Elsevier
These studies describe the role of transition metal ions in the liposomal encapsulation of
topotecan. Liposomes (1, 2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and cholesterol …

Surface-enhanced Raman scattering studies of human transcriptional coactivator p300

GV Pavan Kumar, BA Ashok Reddy, M Arif… - The Journal of …, 2006 - ACS Publications
We report for the first time the surface-enhanced Raman scattering (SERS) studies on p300,
a large multidomain transcriptional coactivator protein. Vibration spectral analysis has been …

Dynamic, nonsink method for the simultaneous determination of drug permeability and binding coefficients in liposomes

KD Fugit, BD Anderson - Molecular pharmaceutics, 2014 - ACS Publications
Drug release from liposomal formulations is governed by a complex interplay of kinetic (ie,
drug permeability) and thermodynamic factors (ie, drug partitioning to the bilayer surface) …

[PDF][PDF] Adapting a fluorescence microscope to perform surface enhanced Raman spectroscopy.

GV Kumar, C Narayana - Current Science (00113891), 2007 - researchgate.net
The methodology to modify a simple fluorescence microscope to perform sophisticated
Surface Enhanced Raman Scattering (SERS) experiments, retaining the primary function of …

[PDF][PDF] Raman spectroscopy: a potential technique in analysis of pharmaceuticals

PP Kalantri, RR Somani, DT Makhija - Der Chemica Sinica, 2010 - researchgate.net
The characterization of drug and drug intermediates is necessary in the drug development
process, particularly in the pharmaceutical industry. Various analytical techniques are …

Live-cell monitoring of the glutathione-triggered release of the anticancer drug topotecan on gold nanoparticles in serum-containing media

M Kim, K Ock, K Cho, SW Joo, SY Lee - Chemical Communications, 2012 - pubs.rsc.org
Live-cell monitoring of the glutathione-triggered release of the anticancer drug topotecan on
gold nanoparticles in serum-containing media - Chemical Communications (RSC Publishing) …