The extracellular matrix (ECM) harbours various signals to control cellular functions and the
materiality of tissues. Most efforts to synthetically reconstitute the matrix by biomaterial …

The discovery that cells secrete extracellular vesicles (EVs), which carry a variety of
regulatory proteins, nucleic acids, and lipids, has shed light on the sophisticated manner by …

Human mesenchymal stromal cells (hMSCs) are mechanically sensitive undergoing
phenotypic alterations when subjected to shear stress, cell aggregation, and substrate …

Enzyme-regulated in situ self-assembly of peptides represents one versatile strategy in the
creation of theranostic agents, which, however, is limited by the strong dependence on …

Extracellular vesicles (EVs) are cornerstones of intercellular communication with exciting
fundamental, clinical, and more broadly biotechnological applications. However, variability …

Rigidity (or stiffness) of materials and extracellular matrix has proven to be one of the most
significant extracellular physicochemical cues that can control diverse cell behaviors, such …

The primary impetus of therapeutic cell encapsulation in the past several decades has been
to broaden the options for donor cell sources by countering against rejection by the host …

Various signals in tissue microenvironments are often unevenly distributed around cells.
Cellular responses to asymmetric cell‐matrix adhesion in a 3D space remain generally …

Recent breakthroughs in developing human-relevant organotypic models led to the building
of highly resemblant tissue constructs that hold immense potential for transplantation, drug …

Dental diseases such as caries and periodontitis have been common public health
problems. Dental disease treatment can be achieved through stem cell-based dental …